FREM2-SNAP29 Fusion FISH Probe
The FREM2-SNAP29 Fusion FISH Probe is used to confirm a fusion of the FREM2 and SNAP29 genes. The fusion of the FREM2 and SNAP29 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FREM2-SNAP29-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FREM2-SNAP29-20-RERE | 20 (40 μL) | 200 μL |
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| FREM2-SNAP29-20-REOR | 20 (40 μL) | 200 μL |
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| FREM2-SNAP29-20-REGO | 20 (40 μL) | 200 μL |
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| FREM2-SNAP29-20-REGR | 20 (40 μL) | 200 μL |
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| FREM2-SNAP29-20-REAQ | 20 (40 μL) | 200 μL |
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| FREM2-SNAP29-20-ORRE | 20 (40 μL) | 200 μL |
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| FREM2-SNAP29-20-OROR | 20 (40 μL) | 200 μL |
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| FREM2-SNAP29-20-ORGO | 20 (40 μL) | 200 μL |
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| FREM2-SNAP29-20-ORAQ | 20 (40 μL) | 200 μL |
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| FREM2-SNAP29-20-GORE | 20 (40 μL) | 200 μL |
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| FREM2-SNAP29-20-GOOR | 20 (40 μL) | 200 μL |
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| FREM2-SNAP29-20-GOGO | 20 (40 μL) | 200 μL |
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| FREM2-SNAP29-20-GOGR | 20 (40 μL) | 200 μL |
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| FREM2-SNAP29-20-GOAQ | 20 (40 μL) | 200 μL |
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| FREM2-SNAP29-20-GRRE | 20 (40 μL) | 200 μL |
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| FREM2-SNAP29-20-GROR | 20 (40 μL) | 200 μL |
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| FREM2-SNAP29-20-GRGO | 20 (40 μL) | 200 μL |
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| FREM2-SNAP29-20-GRGR | 20 (40 μL) | 200 μL |
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| FREM2-SNAP29-20-GRAQ | 20 (40 μL) | 200 μL |
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| FREM2-SNAP29-20-AQRE | 20 (40 μL) | 200 μL |
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| FREM2-SNAP29-20-AQOR | 20 (40 μL) | 200 μL |
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| FREM2-SNAP29-20-AQGO | 20 (40 μL) | 200 μL |
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| FREM2-SNAP29-20-AQGR | 20 (40 μL) | 200 μL |
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| FREM2-SNAP29-20-AQAQ | 20 (40 μL) | 200 μL |
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SNAP29 Gene Summary
This gene, a member of the SNAP25 gene family, encodes a protein involved in multiple membrane trafficking steps. Two other members of this gene family, SNAP23 and SNAP25, encode proteins that bind a syntaxin protein and mediate synaptic vesicle membrane docking and fusion to the plasma membrane. The protein encoded by this gene binds tightly to multiple syntaxins and is localized to intracellular membrane structures rather than to the plasma membrane. While the protein is mostly membrane-bound, a significant fraction of it is found free in the cytoplasm. Use of multiple polyadenylation sites has been noted for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Synaptosome Associated Protein 29
Chromosome: CHR22: 21213291 -21245501
Locus: 22q11.21
FREM2 Gene Summary
This gene encodes an integral membrane protein containing numerous CSPG (chondroitin sulfate proteoglycan element) repeats and Calx-beta domains. The encoded protein localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions. This protein is important for the integrity of skin and renal epithelia. Mutations in this gene are associated with Fraser syndrome. [provided by RefSeq, Apr 2014]
Gene Name: FRAS1 Related Extracellular Matrix Protein 2
Chromosome: CHR13: 39261172 -39461267
Locus: 13q13.3
Gene Diseases
The FREM2 SNAP29 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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