FRAS1-DCK Fusion FISH Probe
The FRAS1-DCK Fusion FISH Probe is used to confirm a fusion of the FRAS1 and DCK genes. The fusion of the FRAS1 and DCK genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FRAS1-DCK-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FRAS1-DCK-20-RERE | 20 (40 μL) | 200 μL |
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| FRAS1-DCK-20-REOR | 20 (40 μL) | 200 μL |
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| FRAS1-DCK-20-REGO | 20 (40 μL) | 200 μL |
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| FRAS1-DCK-20-REGR | 20 (40 μL) | 200 μL |
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| FRAS1-DCK-20-REAQ | 20 (40 μL) | 200 μL |
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| FRAS1-DCK-20-ORRE | 20 (40 μL) | 200 μL |
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| FRAS1-DCK-20-OROR | 20 (40 μL) | 200 μL |
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| FRAS1-DCK-20-ORGO | 20 (40 μL) | 200 μL |
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| FRAS1-DCK-20-ORAQ | 20 (40 μL) | 200 μL |
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| FRAS1-DCK-20-GORE | 20 (40 μL) | 200 μL |
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| FRAS1-DCK-20-GOOR | 20 (40 μL) | 200 μL |
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| FRAS1-DCK-20-GOGO | 20 (40 μL) | 200 μL |
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| FRAS1-DCK-20-GOGR | 20 (40 μL) | 200 μL |
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| FRAS1-DCK-20-GOAQ | 20 (40 μL) | 200 μL |
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| FRAS1-DCK-20-GRRE | 20 (40 μL) | 200 μL |
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| FRAS1-DCK-20-GROR | 20 (40 μL) | 200 μL |
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| FRAS1-DCK-20-GRGO | 20 (40 μL) | 200 μL |
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| FRAS1-DCK-20-GRGR | 20 (40 μL) | 200 μL |
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| FRAS1-DCK-20-GRAQ | 20 (40 μL) | 200 μL |
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| FRAS1-DCK-20-AQRE | 20 (40 μL) | 200 μL |
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| FRAS1-DCK-20-AQOR | 20 (40 μL) | 200 μL |
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| FRAS1-DCK-20-AQGO | 20 (40 μL) | 200 μL |
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| FRAS1-DCK-20-AQGR | 20 (40 μL) | 200 μL |
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| FRAS1-DCK-20-AQAQ | 20 (40 μL) | 200 μL |
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DCK Gene Summary
Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. [provided by RefSeq, Jul 2008]
Gene Name: Deoxycytidine Kinase
Chromosome: CHR4: 71859264 -71896629
Locus: 4q13.3
FRAS1 Gene Summary
This gene encodes an extracellular matrix protein that appears to function in the regulation of epidermal-basement membrane adhesion and organogenesis during development. Mutations in this gene cause Fraser syndrome, a multisystem malformation that can include craniofacial, urogenital and respiratory system abnormalities. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Gene Name: Fraser Extracellular Matrix Complex Subunit 1
Chromosome: CHR4: 78978723 -79465423
Locus: 4q21.21
Gene Diseases
The FRAS1 DCK Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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