FOXP2-EPM2A Fusion FISH Probe
The FOXP2-EPM2A Fusion FISH Probe is used to confirm a fusion of the FOXP2 and EPM2A genes. The fusion of the FOXP2 and EPM2A genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FOXP2-EPM2A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| FOXP2-EPM2A-20-RERE | 20 (40 μL) | 200 μL |
|
|
| FOXP2-EPM2A-20-REOR | 20 (40 μL) | 200 μL |
|
|
| FOXP2-EPM2A-20-REGO | 20 (40 μL) | 200 μL |
|
|
| FOXP2-EPM2A-20-REGR | 20 (40 μL) | 200 μL |
|
|
| FOXP2-EPM2A-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| FOXP2-EPM2A-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| FOXP2-EPM2A-20-OROR | 20 (40 μL) | 200 μL |
|
|
| FOXP2-EPM2A-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| FOXP2-EPM2A-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| FOXP2-EPM2A-20-GORE | 20 (40 μL) | 200 μL |
|
|
| FOXP2-EPM2A-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| FOXP2-EPM2A-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| FOXP2-EPM2A-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| FOXP2-EPM2A-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| FOXP2-EPM2A-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| FOXP2-EPM2A-20-GROR | 20 (40 μL) | 200 μL |
|
|
| FOXP2-EPM2A-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| FOXP2-EPM2A-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| FOXP2-EPM2A-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| FOXP2-EPM2A-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| FOXP2-EPM2A-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| FOXP2-EPM2A-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| FOXP2-EPM2A-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| FOXP2-EPM2A-20-AQAQ | 20 (40 μL) | 200 μL |
|
EPM2A Gene Summary
This gene encodes a dual-specificity phosphatase and may be involved in the regulation of glycogen metabolism. The protein acts on complex carbohydrates to prevent glycogen hyperphosphorylation, thus avoiding the formation of insoluble aggregates. Loss-of-function mutations in this gene have been associated with Lafora disease, a rare, adult-onset recessive neurodegenerative disease, which results in myoclonus epilepsy and usually results in death several years after the onset of symptoms. The disease is characterized by the accumulation of insoluble particles called Lafora bodies, which are derived from glycogen. [provided by RefSeq, Jan 2018]
Gene Name: EPM2A, Laforin Glucan Phosphatase
Chromosome: CHR6: 145946439 -146056991
Locus: 6q24.3
FOXP2 Gene Summary
This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010]
Gene Name: Forkhead Box P2
Chromosome: CHR7: 113726364 -114333827
Locus: 7q31.1
Gene Diseases
The FOXP2 EPM2A Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|