FOXP2-ENKUR Fusion FISH Probe
The FOXP2-ENKUR Fusion FISH Probe is used to confirm a fusion of the FOXP2 and ENKUR genes. The fusion of the FOXP2 and ENKUR genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FOXP2-ENKUR-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FOXP2-ENKUR-20-RERE | 20 (40 μL) | 200 μL |
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| FOXP2-ENKUR-20-REOR | 20 (40 μL) | 200 μL |
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| FOXP2-ENKUR-20-REGO | 20 (40 μL) | 200 μL |
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| FOXP2-ENKUR-20-REGR | 20 (40 μL) | 200 μL |
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| FOXP2-ENKUR-20-REAQ | 20 (40 μL) | 200 μL |
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| FOXP2-ENKUR-20-ORRE | 20 (40 μL) | 200 μL |
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| FOXP2-ENKUR-20-OROR | 20 (40 μL) | 200 μL |
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| FOXP2-ENKUR-20-ORGO | 20 (40 μL) | 200 μL |
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| FOXP2-ENKUR-20-ORAQ | 20 (40 μL) | 200 μL |
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| FOXP2-ENKUR-20-GORE | 20 (40 μL) | 200 μL |
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| FOXP2-ENKUR-20-GOOR | 20 (40 μL) | 200 μL |
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| FOXP2-ENKUR-20-GOGO | 20 (40 μL) | 200 μL |
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| FOXP2-ENKUR-20-GOGR | 20 (40 μL) | 200 μL |
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| FOXP2-ENKUR-20-GOAQ | 20 (40 μL) | 200 μL |
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| FOXP2-ENKUR-20-GRRE | 20 (40 μL) | 200 μL |
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| FOXP2-ENKUR-20-GROR | 20 (40 μL) | 200 μL |
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| FOXP2-ENKUR-20-GRGO | 20 (40 μL) | 200 μL |
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| FOXP2-ENKUR-20-GRGR | 20 (40 μL) | 200 μL |
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| FOXP2-ENKUR-20-GRAQ | 20 (40 μL) | 200 μL |
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| FOXP2-ENKUR-20-AQRE | 20 (40 μL) | 200 μL |
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| FOXP2-ENKUR-20-AQOR | 20 (40 μL) | 200 μL |
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| FOXP2-ENKUR-20-AQGO | 20 (40 μL) | 200 μL |
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| FOXP2-ENKUR-20-AQGR | 20 (40 μL) | 200 μL |
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| FOXP2-ENKUR-20-AQAQ | 20 (40 μL) | 200 μL |
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FOXP2 Gene Summary
This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010]
Gene Name: Forkhead Box P2
Chromosome: CHR7: 113726364 -114333827
Locus: 7q31.1
ENKUR Gene Summary
This gene encodes a protein that interacts with calmodulin and several transient receptor potential canonical cation channel proteins. The encoded protein may function as an adaptor to localize signal transduction machinery to calcium channels. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]
Gene Name: Enkurin, TRPC Channel Interacting Protein
Chromosome: CHR10: 25270916 -25305030
Locus: 10p12.1
Gene Diseases
The FOXP2 ENKUR Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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