FOXN3-KCNQ1 Fusion FISH Probe
The FOXN3-KCNQ1 Fusion FISH Probe is used to confirm a fusion of the FOXN3 and KCNQ1 genes. The fusion of the FOXN3 and KCNQ1 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FOXN3-KCNQ1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FOXN3-KCNQ1-20-RERE | 20 (40 μL) | 200 μL |
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| FOXN3-KCNQ1-20-REOR | 20 (40 μL) | 200 μL |
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| FOXN3-KCNQ1-20-REGO | 20 (40 μL) | 200 μL |
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| FOXN3-KCNQ1-20-REGR | 20 (40 μL) | 200 μL |
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| FOXN3-KCNQ1-20-REAQ | 20 (40 μL) | 200 μL |
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| FOXN3-KCNQ1-20-ORRE | 20 (40 μL) | 200 μL |
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| FOXN3-KCNQ1-20-OROR | 20 (40 μL) | 200 μL |
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| FOXN3-KCNQ1-20-ORGO | 20 (40 μL) | 200 μL |
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| FOXN3-KCNQ1-20-ORAQ | 20 (40 μL) | 200 μL |
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| FOXN3-KCNQ1-20-GORE | 20 (40 μL) | 200 μL |
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| FOXN3-KCNQ1-20-GOOR | 20 (40 μL) | 200 μL |
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| FOXN3-KCNQ1-20-GOGO | 20 (40 μL) | 200 μL |
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| FOXN3-KCNQ1-20-GOGR | 20 (40 μL) | 200 μL |
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| FOXN3-KCNQ1-20-GOAQ | 20 (40 μL) | 200 μL |
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| FOXN3-KCNQ1-20-GRRE | 20 (40 μL) | 200 μL |
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| FOXN3-KCNQ1-20-GROR | 20 (40 μL) | 200 μL |
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| FOXN3-KCNQ1-20-GRGO | 20 (40 μL) | 200 μL |
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| FOXN3-KCNQ1-20-GRGR | 20 (40 μL) | 200 μL |
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| FOXN3-KCNQ1-20-GRAQ | 20 (40 μL) | 200 μL |
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| FOXN3-KCNQ1-20-AQRE | 20 (40 μL) | 200 μL |
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| FOXN3-KCNQ1-20-AQOR | 20 (40 μL) | 200 μL |
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| FOXN3-KCNQ1-20-AQGO | 20 (40 μL) | 200 μL |
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| FOXN3-KCNQ1-20-AQGR | 20 (40 μL) | 200 μL |
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| FOXN3-KCNQ1-20-AQAQ | 20 (40 μL) | 200 μL |
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FOXN3 Gene Summary
This gene is a member of the forkhead/winged helix transcription factor family. Checkpoints are eukaryotic DNA damage-inducible cell cycle arrests at G1 and G2. Checkpoint suppressor 1 suppresses multiple yeast checkpoint mutations including mec1, rad9, rad53 and dun1 by activating a MEC1-independent checkpoint pathway. Alternative splicing is observed at the locus, resulting in distinct isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Forkhead Box N3
Chromosome: CHR14: 89622515 -90085494
Locus: 14q31.3-q32.11
KCNQ1 Gene Summary
This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation. This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others. This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS), and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2011]
Gene Name: Potassium Voltage-gated Channel Subfamily Q Member 1
Chromosome: CHR11: 2466220 -2870340
Locus: 11p15.5-p15.4
Gene Diseases
The FOXN3 KCNQ1 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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