FOXN2-SPTBN1 Fusion FISH Probe
The FOXN2-SPTBN1 Fusion FISH Probe is used to confirm a fusion of the FOXN2 and SPTBN1 genes. The fusion of the FOXN2 and SPTBN1 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FOXN2-SPTBN1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FOXN2-SPTBN1-20-RERE | 20 (40 μL) | 200 μL |
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| FOXN2-SPTBN1-20-REOR | 20 (40 μL) | 200 μL |
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| FOXN2-SPTBN1-20-REGO | 20 (40 μL) | 200 μL |
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| FOXN2-SPTBN1-20-REGR | 20 (40 μL) | 200 μL |
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| FOXN2-SPTBN1-20-REAQ | 20 (40 μL) | 200 μL |
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| FOXN2-SPTBN1-20-ORRE | 20 (40 μL) | 200 μL |
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| FOXN2-SPTBN1-20-OROR | 20 (40 μL) | 200 μL |
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| FOXN2-SPTBN1-20-ORGO | 20 (40 μL) | 200 μL |
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| FOXN2-SPTBN1-20-ORAQ | 20 (40 μL) | 200 μL |
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| FOXN2-SPTBN1-20-GORE | 20 (40 μL) | 200 μL |
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| FOXN2-SPTBN1-20-GOOR | 20 (40 μL) | 200 μL |
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| FOXN2-SPTBN1-20-GOGO | 20 (40 μL) | 200 μL |
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| FOXN2-SPTBN1-20-GOGR | 20 (40 μL) | 200 μL |
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| FOXN2-SPTBN1-20-GOAQ | 20 (40 μL) | 200 μL |
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| FOXN2-SPTBN1-20-GRRE | 20 (40 μL) | 200 μL |
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| FOXN2-SPTBN1-20-GROR | 20 (40 μL) | 200 μL |
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| FOXN2-SPTBN1-20-GRGO | 20 (40 μL) | 200 μL |
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| FOXN2-SPTBN1-20-GRGR | 20 (40 μL) | 200 μL |
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| FOXN2-SPTBN1-20-GRAQ | 20 (40 μL) | 200 μL |
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| FOXN2-SPTBN1-20-AQRE | 20 (40 μL) | 200 μL |
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| FOXN2-SPTBN1-20-AQOR | 20 (40 μL) | 200 μL |
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| FOXN2-SPTBN1-20-AQGO | 20 (40 μL) | 200 μL |
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| FOXN2-SPTBN1-20-AQGR | 20 (40 μL) | 200 μL |
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| FOXN2-SPTBN1-20-AQAQ | 20 (40 μL) | 200 μL |
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FOXN2 Gene Summary
This gene encodes a forkhead domain binding protein and may function in the transcriptional regulation of the human T-cell leukemia virus long terminal repeat. [provided by RefSeq, Jul 2008]
Gene Name: Forkhead Box N2
Chromosome: CHR2: 48541794 -48606434
Locus: 2p16.3
SPTBN1 Gene Summary
Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. This gene is one member of a family of beta-spectrin genes. The encoded protein contains an N-terminal actin-binding domain, and 17 spectrin repeats which are involved in dimer formation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Spectrin Beta, Non-erythrocytic 1
Chromosome: CHR2: 54683453 -54898583
Locus: 2p16.2
Gene Diseases
The FOXN2 SPTBN1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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