FOXK2-TNFSF12-TNFSF13 Fusion FISH Probe
The FOXK2-TNFSF12-TNFSF13 Fusion FISH Probe is used to confirm a fusion of the FOXK2 and TNFSF12-TNFSF13 genes. The fusion of the FOXK2 and TNFSF12-TNFSF13 genes has been associated with Adrenocortical Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FOXK2-TNFSF12-TNFSF13-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FOXK2-TNFSF12-TNFSF13-20-RERE | 20 (40 μL) | 200 μL |
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| FOXK2-TNFSF12-TNFSF13-20-REOR | 20 (40 μL) | 200 μL |
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| FOXK2-TNFSF12-TNFSF13-20-REGO | 20 (40 μL) | 200 μL |
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| FOXK2-TNFSF12-TNFSF13-20-REGR | 20 (40 μL) | 200 μL |
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| FOXK2-TNFSF12-TNFSF13-20-REAQ | 20 (40 μL) | 200 μL |
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| FOXK2-TNFSF12-TNFSF13-20-ORRE | 20 (40 μL) | 200 μL |
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| FOXK2-TNFSF12-TNFSF13-20-OROR | 20 (40 μL) | 200 μL |
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| FOXK2-TNFSF12-TNFSF13-20-ORGO | 20 (40 μL) | 200 μL |
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| FOXK2-TNFSF12-TNFSF13-20-ORAQ | 20 (40 μL) | 200 μL |
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| FOXK2-TNFSF12-TNFSF13-20-GORE | 20 (40 μL) | 200 μL |
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| FOXK2-TNFSF12-TNFSF13-20-GOOR | 20 (40 μL) | 200 μL |
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| FOXK2-TNFSF12-TNFSF13-20-GOGO | 20 (40 μL) | 200 μL |
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| FOXK2-TNFSF12-TNFSF13-20-GOGR | 20 (40 μL) | 200 μL |
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| FOXK2-TNFSF12-TNFSF13-20-GOAQ | 20 (40 μL) | 200 μL |
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| FOXK2-TNFSF12-TNFSF13-20-GRRE | 20 (40 μL) | 200 μL |
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| FOXK2-TNFSF12-TNFSF13-20-GROR | 20 (40 μL) | 200 μL |
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| FOXK2-TNFSF12-TNFSF13-20-GRGO | 20 (40 μL) | 200 μL |
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| FOXK2-TNFSF12-TNFSF13-20-GRGR | 20 (40 μL) | 200 μL |
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| FOXK2-TNFSF12-TNFSF13-20-GRAQ | 20 (40 μL) | 200 μL |
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| FOXK2-TNFSF12-TNFSF13-20-AQRE | 20 (40 μL) | 200 μL |
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| FOXK2-TNFSF12-TNFSF13-20-AQOR | 20 (40 μL) | 200 μL |
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| FOXK2-TNFSF12-TNFSF13-20-AQGO | 20 (40 μL) | 200 μL |
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| FOXK2-TNFSF12-TNFSF13-20-AQGR | 20 (40 μL) | 200 μL |
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| FOXK2-TNFSF12-TNFSF13-20-AQAQ | 20 (40 μL) | 200 μL |
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FOXK2 Gene Summary
The protein encoded by this gene contains a fork head DNA binding domain. This protein can bind to the purine-rich motifs of the HIV long terminal repeat (LTR), and to the similar purine-rich motif in the interleukin 2 (IL2) promoter. It may be involved in the regulation of viral and cellular promoter elements. [provided by RefSeq, Jul 2008]
Gene Name: Forkhead Box K2
Chromosome: CHR17: 80477593 -80562483
Locus: 17q25.3
TNFSF12-TNFSF13 Gene Summary
This gene encodes a member of the tumor necrosis factor superfamily. It encodes a hybrid protein composed of the cytoplasmic and transmembrane domains of family member 12 fused to the C-terminal domain of family member 13. The hybrid protein is membrane anchored and presents the receptor-binding domain of family member 13 at the cell surface. It stimulates cycling in T- and B-lymphoma cell lines. [provided by RefSeq, Jul 2008]
Gene Name: TNFSF12-TNFSF13 Readthrough
Chromosome: CHR17: 7452374 -7464925
Locus: 17p13.1
Gene Diseases
The FOXK2 TNFSF12-TNFSF13 Fusion has been associated with the following diseases:
| Disease Name |
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| Adrenocortical Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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