FOXK2-MS4A12 Fusion FISH Probe
The FOXK2-MS4A12 Fusion FISH Probe is used to confirm a fusion of the FOXK2 and MS4A12 genes. The fusion of the FOXK2 and MS4A12 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FOXK2-MS4A12-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FOXK2-MS4A12-20-RERE | 20 (40 μL) | 200 μL |
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| FOXK2-MS4A12-20-REOR | 20 (40 μL) | 200 μL |
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| FOXK2-MS4A12-20-REGO | 20 (40 μL) | 200 μL |
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| FOXK2-MS4A12-20-REGR | 20 (40 μL) | 200 μL |
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| FOXK2-MS4A12-20-REAQ | 20 (40 μL) | 200 μL |
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| FOXK2-MS4A12-20-ORRE | 20 (40 μL) | 200 μL |
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| FOXK2-MS4A12-20-OROR | 20 (40 μL) | 200 μL |
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| FOXK2-MS4A12-20-ORGO | 20 (40 μL) | 200 μL |
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| FOXK2-MS4A12-20-ORAQ | 20 (40 μL) | 200 μL |
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| FOXK2-MS4A12-20-GORE | 20 (40 μL) | 200 μL |
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| FOXK2-MS4A12-20-GOOR | 20 (40 μL) | 200 μL |
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| FOXK2-MS4A12-20-GOGO | 20 (40 μL) | 200 μL |
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| FOXK2-MS4A12-20-GOGR | 20 (40 μL) | 200 μL |
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| FOXK2-MS4A12-20-GOAQ | 20 (40 μL) | 200 μL |
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| FOXK2-MS4A12-20-GRRE | 20 (40 μL) | 200 μL |
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| FOXK2-MS4A12-20-GROR | 20 (40 μL) | 200 μL |
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| FOXK2-MS4A12-20-GRGO | 20 (40 μL) | 200 μL |
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| FOXK2-MS4A12-20-GRGR | 20 (40 μL) | 200 μL |
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| FOXK2-MS4A12-20-GRAQ | 20 (40 μL) | 200 μL |
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| FOXK2-MS4A12-20-AQRE | 20 (40 μL) | 200 μL |
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| FOXK2-MS4A12-20-AQOR | 20 (40 μL) | 200 μL |
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| FOXK2-MS4A12-20-AQGO | 20 (40 μL) | 200 μL |
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| FOXK2-MS4A12-20-AQGR | 20 (40 μL) | 200 μL |
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| FOXK2-MS4A12-20-AQAQ | 20 (40 μL) | 200 μL |
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FOXK2 Gene Summary
The protein encoded by this gene contains a fork head DNA binding domain. This protein can bind to the purine-rich motifs of the HIV long terminal repeat (LTR), and to the similar purine-rich motif in the interleukin 2 (IL2) promoter. It may be involved in the regulation of viral and cellular promoter elements. [provided by RefSeq, Jul 2008]
Gene Name: Forkhead Box K2
Chromosome: CHR17: 80477593 -80562483
Locus: 17q25.3
MS4A12 Gene Summary
The protein encoded by this gene is a cell surface protein found primarily in the apical membrane of colonocytes. Silencing of this gene in colon cancer cells inhibits the proliferation, cell motility, and chemotactic invasion of cells. This gene is part of a cluster of similar genes found on chromosome 11. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]
Gene Name: Membrane Spanning 4-domains A12
Chromosome: CHR11: 60260250 -60274901
Locus: 11q12.2
Gene Diseases
The FOXK2 MS4A12 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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