FOXK2-ABCA5 Fusion FISH Probe
The FOXK2-ABCA5 Fusion FISH Probe is used to confirm a fusion of the FOXK2 and ABCA5 genes. The fusion of the FOXK2 and ABCA5 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FOXK2-ABCA5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| FOXK2-ABCA5-20-RERE | 20 (40 μL) | 200 μL |
|
|
| FOXK2-ABCA5-20-REOR | 20 (40 μL) | 200 μL |
|
|
| FOXK2-ABCA5-20-REGO | 20 (40 μL) | 200 μL |
|
|
| FOXK2-ABCA5-20-REGR | 20 (40 μL) | 200 μL |
|
|
| FOXK2-ABCA5-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| FOXK2-ABCA5-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| FOXK2-ABCA5-20-OROR | 20 (40 μL) | 200 μL |
|
|
| FOXK2-ABCA5-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| FOXK2-ABCA5-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| FOXK2-ABCA5-20-GORE | 20 (40 μL) | 200 μL |
|
|
| FOXK2-ABCA5-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| FOXK2-ABCA5-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| FOXK2-ABCA5-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| FOXK2-ABCA5-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| FOXK2-ABCA5-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| FOXK2-ABCA5-20-GROR | 20 (40 μL) | 200 μL |
|
|
| FOXK2-ABCA5-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| FOXK2-ABCA5-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| FOXK2-ABCA5-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| FOXK2-ABCA5-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| FOXK2-ABCA5-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| FOXK2-ABCA5-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| FOXK2-ABCA5-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| FOXK2-ABCA5-20-AQAQ | 20 (40 μL) | 200 μL |
|
FOXK2 Gene Summary
The protein encoded by this gene contains a fork head DNA binding domain. This protein can bind to the purine-rich motifs of the HIV long terminal repeat (LTR), and to the similar purine-rich motif in the interleukin 2 (IL2) promoter. It may be involved in the regulation of viral and cellular promoter elements. [provided by RefSeq, Jul 2008]
Gene Name: Forkhead Box K2
Chromosome: CHR17: 80477593 -80562483
Locus: 17q25.3
ABCA5 Gene Summary
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This gene is clustered among 4 other ABC1 family members on 17q24, but neither the substrate nor the function of this gene is known. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]
Gene Name: ATP Binding Cassette Subfamily A Member 5
Chromosome: CHR17: 67240575 -67323323
Locus: 17q24.3
Gene Diseases
The FOXK2 ABCA5 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|