FOXA3-RGS6 Fusion FISH Probe
The FOXA3-RGS6 Fusion FISH Probe is used to confirm a fusion of the FOXA3 and RGS6 genes. The fusion of the FOXA3 and RGS6 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FOXA3-RGS6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| FOXA3-RGS6-20-RERE | 20 (40 μL) | 200 μL |
|
|
| FOXA3-RGS6-20-REOR | 20 (40 μL) | 200 μL |
|
|
| FOXA3-RGS6-20-REGO | 20 (40 μL) | 200 μL |
|
|
| FOXA3-RGS6-20-REGR | 20 (40 μL) | 200 μL |
|
|
| FOXA3-RGS6-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| FOXA3-RGS6-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| FOXA3-RGS6-20-OROR | 20 (40 μL) | 200 μL |
|
|
| FOXA3-RGS6-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| FOXA3-RGS6-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| FOXA3-RGS6-20-GORE | 20 (40 μL) | 200 μL |
|
|
| FOXA3-RGS6-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| FOXA3-RGS6-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| FOXA3-RGS6-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| FOXA3-RGS6-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| FOXA3-RGS6-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| FOXA3-RGS6-20-GROR | 20 (40 μL) | 200 μL |
|
|
| FOXA3-RGS6-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| FOXA3-RGS6-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| FOXA3-RGS6-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| FOXA3-RGS6-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| FOXA3-RGS6-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| FOXA3-RGS6-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| FOXA3-RGS6-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| FOXA3-RGS6-20-AQAQ | 20 (40 μL) | 200 μL |
|
FOXA3 Gene Summary
This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. The crystal structure of a similar protein in rat has been resolved. [provided by RefSeq, Jul 2008]
Gene Name: Forkhead Box A3
Chromosome: CHR19: 46367517 -46377055
Locus: 19q13.32
RGS6 Gene Summary
This gene encodes a member of the RGS (regulator of G protein signaling) family of proteins, which are defined by the presence of a RGS domain that confers the GTPase-activating activity of these proteins toward certain G alpha subunits. This protein also belongs to a subfamily of RGS proteins characterized by the presence of DEP and GGL domains, the latter a G beta 5-interacting domain. The RGS proteins negatively regulate G protein signaling, and may modulate neuronal, cardiovascular, lymphocytic activities, and cancer risk. Many alternatively spliced transcript variants encoding different isoforms with long or short N-terminal domains, complete or incomplete GGL domains, and distinct C-terminal domains, have been described for this gene, however, the full-length nature of some of these variants is not known.[provided by RefSeq, Mar 2011]
Gene Name: Regulator Of G Protein Signaling 6
Chromosome: CHR14: 72398816 -73033238
Locus: 14q24.2
Gene Diseases
The FOXA3 RGS6 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|