FOSB-ITPKC Fusion FISH Probe
The FOSB-ITPKC Fusion FISH Probe is used to confirm a fusion of the FOSB and ITPKC genes. The fusion of the FOSB and ITPKC genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FOSB-ITPKC-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| FOSB-ITPKC-20-RERE | 20 (40 μL) | 200 μL |
|
|
| FOSB-ITPKC-20-REOR | 20 (40 μL) | 200 μL |
|
|
| FOSB-ITPKC-20-REGO | 20 (40 μL) | 200 μL |
|
|
| FOSB-ITPKC-20-REGR | 20 (40 μL) | 200 μL |
|
|
| FOSB-ITPKC-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| FOSB-ITPKC-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| FOSB-ITPKC-20-OROR | 20 (40 μL) | 200 μL |
|
|
| FOSB-ITPKC-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| FOSB-ITPKC-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| FOSB-ITPKC-20-GORE | 20 (40 μL) | 200 μL |
|
|
| FOSB-ITPKC-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| FOSB-ITPKC-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| FOSB-ITPKC-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| FOSB-ITPKC-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| FOSB-ITPKC-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| FOSB-ITPKC-20-GROR | 20 (40 μL) | 200 μL |
|
|
| FOSB-ITPKC-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| FOSB-ITPKC-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| FOSB-ITPKC-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| FOSB-ITPKC-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| FOSB-ITPKC-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| FOSB-ITPKC-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| FOSB-ITPKC-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| FOSB-ITPKC-20-AQAQ | 20 (40 μL) | 200 μL |
|
FOSB Gene Summary
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: FosB Proto-oncogene, AP-1 Transcription Factor Subunit
Chromosome: CHR19: 45971252 -45978437
Locus: 19q13.32
ITPKC Gene Summary
This gene encodes a member of the inositol 1,4,5-trisphosphate [Ins(1,4,5)P(3)] 3-kinase family of enzymes that catalyze the phosphorylation of inositol 1,4,5-trisphosphate to 1,3,4,5-tetrakisphosphate. The encoded protein is localized to the nucleus and cytoplasm and has both nuclear import and nuclear export activity. Single nucleotide polymorphisms in this gene are associated with Kawasaki disease.[provided by RefSeq, Sep 2009]
Gene Name: Inositol-trisphosphate 3-kinase C
Chromosome: CHR19: 41223007 -41246765
Locus: 19q13.2
Gene Diseases
The FOSB ITPKC Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|