FNIP2-LARP7 Fusion FISH Probe
The FNIP2-LARP7 Fusion FISH Probe is used to confirm a fusion of the FNIP2 and LARP7 genes. The fusion of the FNIP2 and LARP7 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FNIP2-LARP7-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FNIP2-LARP7-20-RERE | 20 (40 μL) | 200 μL |
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| FNIP2-LARP7-20-REOR | 20 (40 μL) | 200 μL |
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| FNIP2-LARP7-20-REGO | 20 (40 μL) | 200 μL |
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| FNIP2-LARP7-20-REGR | 20 (40 μL) | 200 μL |
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| FNIP2-LARP7-20-REAQ | 20 (40 μL) | 200 μL |
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| FNIP2-LARP7-20-ORRE | 20 (40 μL) | 200 μL |
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| FNIP2-LARP7-20-OROR | 20 (40 μL) | 200 μL |
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| FNIP2-LARP7-20-ORGO | 20 (40 μL) | 200 μL |
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| FNIP2-LARP7-20-ORAQ | 20 (40 μL) | 200 μL |
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| FNIP2-LARP7-20-GORE | 20 (40 μL) | 200 μL |
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| FNIP2-LARP7-20-GOOR | 20 (40 μL) | 200 μL |
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| FNIP2-LARP7-20-GOGO | 20 (40 μL) | 200 μL |
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| FNIP2-LARP7-20-GOGR | 20 (40 μL) | 200 μL |
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| FNIP2-LARP7-20-GOAQ | 20 (40 μL) | 200 μL |
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| FNIP2-LARP7-20-GRRE | 20 (40 μL) | 200 μL |
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| FNIP2-LARP7-20-GROR | 20 (40 μL) | 200 μL |
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| FNIP2-LARP7-20-GRGO | 20 (40 μL) | 200 μL |
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| FNIP2-LARP7-20-GRGR | 20 (40 μL) | 200 μL |
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| FNIP2-LARP7-20-GRAQ | 20 (40 μL) | 200 μL |
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| FNIP2-LARP7-20-AQRE | 20 (40 μL) | 200 μL |
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| FNIP2-LARP7-20-AQOR | 20 (40 μL) | 200 μL |
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| FNIP2-LARP7-20-AQGO | 20 (40 μL) | 200 μL |
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| FNIP2-LARP7-20-AQGR | 20 (40 μL) | 200 μL |
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| FNIP2-LARP7-20-AQAQ | 20 (40 μL) | 200 μL |
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LARP7 Gene Summary
This gene encodes a protein which is found in the 7SK snRNP (small nuclear ribonucleoprotein). This snRNP complex inhibits a cyclin-dependent kinase, positive transcription elongation factor b, which is required for paused RNA polymerase II at a promoter to begin transcription elongation. A pseudogene of this gene is located on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2012]
Gene Name: La Ribonucleoprotein Domain Family Member 7
Chromosome: CHR4: 113558119 -113578742
Locus: 4q25
FNIP2 Gene Summary
This gene encodes a protein that binds to the tumor suppressor folliculin and to AMP-activated protein kinase (AMPK), and may play a role cellular metabolism and nutrient sensing by regulating the AMPK-mechanistic target of rapamycin signaling pathway. The encoded protein may also be involved in regulating the O6-methylguanine-induced apoptosis signaling pathway. This gene has a closely related paralog that encodes a protein with similar binding activities. Both related proteins also associate with the molecular chaperone heat shock protein-90 (Hsp90) and negatively regulate its ATPase activity and facilitate its association with folliculin. [provided by RefSeq, Jul 2017]
Gene Name: Folliculin Interacting Protein 2
Chromosome: CHR4: 159690181 -159827954
Locus: 4q32.1
Gene Diseases
The FNIP2 LARP7 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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