FNIP1-AHDC1 Fusion FISH Probe
The FNIP1-AHDC1 Fusion FISH Probe is used to confirm a fusion of the FNIP1 and AHDC1 genes. The fusion of the FNIP1 and AHDC1 genes has been associated with Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FNIP1-AHDC1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FNIP1-AHDC1-20-RERE | 20 (40 μL) | 200 μL |
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| FNIP1-AHDC1-20-REOR | 20 (40 μL) | 200 μL |
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| FNIP1-AHDC1-20-REGO | 20 (40 μL) | 200 μL |
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| FNIP1-AHDC1-20-REGR | 20 (40 μL) | 200 μL |
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| FNIP1-AHDC1-20-REAQ | 20 (40 μL) | 200 μL |
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| FNIP1-AHDC1-20-ORRE | 20 (40 μL) | 200 μL |
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| FNIP1-AHDC1-20-OROR | 20 (40 μL) | 200 μL |
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| FNIP1-AHDC1-20-ORGO | 20 (40 μL) | 200 μL |
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| FNIP1-AHDC1-20-ORAQ | 20 (40 μL) | 200 μL |
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| FNIP1-AHDC1-20-GORE | 20 (40 μL) | 200 μL |
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| FNIP1-AHDC1-20-GOOR | 20 (40 μL) | 200 μL |
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| FNIP1-AHDC1-20-GOGO | 20 (40 μL) | 200 μL |
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| FNIP1-AHDC1-20-GOGR | 20 (40 μL) | 200 μL |
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| FNIP1-AHDC1-20-GOAQ | 20 (40 μL) | 200 μL |
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| FNIP1-AHDC1-20-GRRE | 20 (40 μL) | 200 μL |
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| FNIP1-AHDC1-20-GROR | 20 (40 μL) | 200 μL |
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| FNIP1-AHDC1-20-GRGO | 20 (40 μL) | 200 μL |
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| FNIP1-AHDC1-20-GRGR | 20 (40 μL) | 200 μL |
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| FNIP1-AHDC1-20-GRAQ | 20 (40 μL) | 200 μL |
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| FNIP1-AHDC1-20-AQRE | 20 (40 μL) | 200 μL |
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| FNIP1-AHDC1-20-AQOR | 20 (40 μL) | 200 μL |
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| FNIP1-AHDC1-20-AQGO | 20 (40 μL) | 200 μL |
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| FNIP1-AHDC1-20-AQGR | 20 (40 μL) | 200 μL |
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| FNIP1-AHDC1-20-AQAQ | 20 (40 μL) | 200 μL |
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AHDC1 Gene Summary
This gene encodes a protein containing two AT-hooks, which likely function in DNA binding. Mutations in this gene were found in individuals with Xia-Gibbs syndrome. [provided by RefSeq, Jun 2014]
Gene Name: AT-hook DNA Binding Motif Containing 1
Chromosome: CHR1: 27860755 -27930143
Locus: 1p36.11-p35.3
FNIP1 Gene Summary
This gene encodes a protein that binds to the tumor suppressor protein folliculin and to AMP-activated protein kinase (AMPK). The encoded protein participates in the regulation of cellular metabolism and nutrient sensing by modulating the AMPK and target of rapamycin signaling pathways. This gene has a closely related paralog that encodes a protein with similar binding activities. Both related proteins also associate with the molecular chaperone heat shock protein-90 (Hsp90) and negatively regulate its ATPase activity and facilitate its association with folliculin. [provided by RefSeq, Jul 2017]
Gene Name: Folliculin Interacting Protein 1
Chromosome: CHR5: 130977406 -131132756
Locus: 5q31.1
Gene Diseases
The FNIP1 AHDC1 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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