FN3KRP-KCNQ1 Fusion FISH Probe
The FN3KRP-KCNQ1 Fusion FISH Probe is used to confirm a fusion of the FN3KRP and KCNQ1 genes. The fusion of the FN3KRP and KCNQ1 genes has been associated with Adrenocortical Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FN3KRP-KCNQ1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| FN3KRP-KCNQ1-20-RERE | 20 (40 μL) | 200 μL |
|
|
| FN3KRP-KCNQ1-20-REOR | 20 (40 μL) | 200 μL |
|
|
| FN3KRP-KCNQ1-20-REGO | 20 (40 μL) | 200 μL |
|
|
| FN3KRP-KCNQ1-20-REGR | 20 (40 μL) | 200 μL |
|
|
| FN3KRP-KCNQ1-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| FN3KRP-KCNQ1-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| FN3KRP-KCNQ1-20-OROR | 20 (40 μL) | 200 μL |
|
|
| FN3KRP-KCNQ1-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| FN3KRP-KCNQ1-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| FN3KRP-KCNQ1-20-GORE | 20 (40 μL) | 200 μL |
|
|
| FN3KRP-KCNQ1-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| FN3KRP-KCNQ1-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| FN3KRP-KCNQ1-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| FN3KRP-KCNQ1-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| FN3KRP-KCNQ1-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| FN3KRP-KCNQ1-20-GROR | 20 (40 μL) | 200 μL |
|
|
| FN3KRP-KCNQ1-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| FN3KRP-KCNQ1-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| FN3KRP-KCNQ1-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| FN3KRP-KCNQ1-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| FN3KRP-KCNQ1-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| FN3KRP-KCNQ1-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| FN3KRP-KCNQ1-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| FN3KRP-KCNQ1-20-AQAQ | 20 (40 μL) | 200 μL |
|
KCNQ1 Gene Summary
This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation. This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others. This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS), and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2011]
Gene Name: Potassium Voltage-gated Channel Subfamily Q Member 1
Chromosome: CHR11: 2466220 -2870340
Locus: 11p15.5-p15.4
FN3KRP Gene Summary
A high concentration of glucose can result in non-enzymatic oxidation of proteins by reaction of glucose and lysine residues (glycation). Proteins modified in this way are less active or functional. This gene encodes an enzyme which catalyzes the phosphorylation of psicosamines and ribulosamines compared to the neighboring gene which encodes a highly similar enzyme, fructosamine-3-kinase, which has different substrate specificity. The activity of both enzymes may result in deglycation of proteins to restore their function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012]
Gene Name: Fructosamine 3 Kinase Related Protein
Chromosome: CHR17: 80674581 -80685893
Locus: 17q25.3
Gene Diseases
The FN3KRP KCNQ1 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Adrenocortical Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|