FN1-ARFGEF2 Fusion FISH Probe
The FN1-ARFGEF2 Fusion FISH Probe is used to confirm a fusion of the FN1 and ARFGEF2 genes. The fusion of the FN1 and ARFGEF2 genes has been associated with Thyroid Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FN1-ARFGEF2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FN1-ARFGEF2-20-RERE | 20 (40 μL) | 200 μL |
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| FN1-ARFGEF2-20-REOR | 20 (40 μL) | 200 μL |
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| FN1-ARFGEF2-20-REGO | 20 (40 μL) | 200 μL |
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| FN1-ARFGEF2-20-REGR | 20 (40 μL) | 200 μL |
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| FN1-ARFGEF2-20-REAQ | 20 (40 μL) | 200 μL |
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| FN1-ARFGEF2-20-ORRE | 20 (40 μL) | 200 μL |
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| FN1-ARFGEF2-20-OROR | 20 (40 μL) | 200 μL |
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| FN1-ARFGEF2-20-ORGO | 20 (40 μL) | 200 μL |
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| FN1-ARFGEF2-20-ORAQ | 20 (40 μL) | 200 μL |
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| FN1-ARFGEF2-20-GORE | 20 (40 μL) | 200 μL |
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| FN1-ARFGEF2-20-GOOR | 20 (40 μL) | 200 μL |
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| FN1-ARFGEF2-20-GOGO | 20 (40 μL) | 200 μL |
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| FN1-ARFGEF2-20-GOGR | 20 (40 μL) | 200 μL |
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| FN1-ARFGEF2-20-GOAQ | 20 (40 μL) | 200 μL |
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| FN1-ARFGEF2-20-GRRE | 20 (40 μL) | 200 μL |
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| FN1-ARFGEF2-20-GROR | 20 (40 μL) | 200 μL |
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| FN1-ARFGEF2-20-GRGO | 20 (40 μL) | 200 μL |
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| FN1-ARFGEF2-20-GRGR | 20 (40 μL) | 200 μL |
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| FN1-ARFGEF2-20-GRAQ | 20 (40 μL) | 200 μL |
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| FN1-ARFGEF2-20-AQRE | 20 (40 μL) | 200 μL |
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| FN1-ARFGEF2-20-AQOR | 20 (40 μL) | 200 μL |
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| FN1-ARFGEF2-20-AQGO | 20 (40 μL) | 200 μL |
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| FN1-ARFGEF2-20-AQGR | 20 (40 μL) | 200 μL |
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| FN1-ARFGEF2-20-AQAQ | 20 (40 μL) | 200 μL |
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FN1 Gene Summary
This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. The encoded preproprotein is proteolytically processed to generate the mature protein. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing. The full-length nature of some variants has not been determined. [provided by RefSeq, Jan 2016]
Gene Name: Fibronectin 1
Chromosome: CHR2: 216225178 -216300791
Locus: 2q35
ARFGEF2 Gene Summary
ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine-nucleotide exchange activity and also brefeldin A inhibition. [provided by RefSeq, Jul 2008]
Gene Name: ADP Ribosylation Factor Guanine Nucleotide Exchange Factor 2
Chromosome: CHR20: 47538274 -47653230
Locus: 20q13.13
Gene Diseases
The FN1 ARFGEF2 Fusion has been associated with the following diseases:
| Disease Name |
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| Thyroid Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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