FMOD-ARFGEF2 Fusion FISH Probe
The FMOD-ARFGEF2 Fusion FISH Probe is used to confirm a fusion of the FMOD and ARFGEF2 genes. The fusion of the FMOD and ARFGEF2 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FMOD-ARFGEF2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FMOD-ARFGEF2-20-RERE | 20 (40 μL) | 200 μL |
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| FMOD-ARFGEF2-20-REOR | 20 (40 μL) | 200 μL |
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| FMOD-ARFGEF2-20-REGO | 20 (40 μL) | 200 μL |
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| FMOD-ARFGEF2-20-REGR | 20 (40 μL) | 200 μL |
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| FMOD-ARFGEF2-20-REAQ | 20 (40 μL) | 200 μL |
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| FMOD-ARFGEF2-20-ORRE | 20 (40 μL) | 200 μL |
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| FMOD-ARFGEF2-20-OROR | 20 (40 μL) | 200 μL |
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| FMOD-ARFGEF2-20-ORGO | 20 (40 μL) | 200 μL |
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| FMOD-ARFGEF2-20-ORAQ | 20 (40 μL) | 200 μL |
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| FMOD-ARFGEF2-20-GORE | 20 (40 μL) | 200 μL |
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| FMOD-ARFGEF2-20-GOOR | 20 (40 μL) | 200 μL |
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| FMOD-ARFGEF2-20-GOGO | 20 (40 μL) | 200 μL |
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| FMOD-ARFGEF2-20-GOGR | 20 (40 μL) | 200 μL |
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| FMOD-ARFGEF2-20-GOAQ | 20 (40 μL) | 200 μL |
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| FMOD-ARFGEF2-20-GRRE | 20 (40 μL) | 200 μL |
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| FMOD-ARFGEF2-20-GROR | 20 (40 μL) | 200 μL |
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| FMOD-ARFGEF2-20-GRGO | 20 (40 μL) | 200 μL |
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| FMOD-ARFGEF2-20-GRGR | 20 (40 μL) | 200 μL |
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| FMOD-ARFGEF2-20-GRAQ | 20 (40 μL) | 200 μL |
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| FMOD-ARFGEF2-20-AQRE | 20 (40 μL) | 200 μL |
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| FMOD-ARFGEF2-20-AQOR | 20 (40 μL) | 200 μL |
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| FMOD-ARFGEF2-20-AQGO | 20 (40 μL) | 200 μL |
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| FMOD-ARFGEF2-20-AQGR | 20 (40 μL) | 200 μL |
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| FMOD-ARFGEF2-20-AQAQ | 20 (40 μL) | 200 μL |
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FMOD Gene Summary
Fibromodulin belongs to the family of small interstitial proteoglycans. The encoded protein possesses a central region containing leucine-rich repeats with 4 keratan sulfate chains, flanked by terminal domains containing disulphide bonds. Owing to the interaction with type I and type II collagen fibrils and in vitro inhibition of fibrillogenesis, the encoded protein may play a role in the assembly of extracellular matrix. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Sequence variations in this gene may be associated with the pathogenesis of high myopia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
Gene Name: Fibromodulin
Chromosome: CHR1: 203309751 -203320289
Locus: 1q32.1
ARFGEF2 Gene Summary
ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine-nucleotide exchange activity and also brefeldin A inhibition. [provided by RefSeq, Jul 2008]
Gene Name: ADP Ribosylation Factor Guanine Nucleotide Exchange Factor 2
Chromosome: CHR20: 47538274 -47653230
Locus: 20q13.13
Gene Diseases
The FMOD ARFGEF2 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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