FLT3LG-ALDH16A1 Fusion FISH Probe
The FLT3LG-ALDH16A1 Fusion FISH Probe is used to confirm a fusion of the FLT3LG and ALDH16A1 genes. The fusion of the FLT3LG and ALDH16A1 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FLT3LG-ALDH16A1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FLT3LG-ALDH16A1-20-RERE | 20 (40 μL) | 200 μL |
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| FLT3LG-ALDH16A1-20-REOR | 20 (40 μL) | 200 μL |
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| FLT3LG-ALDH16A1-20-REGO | 20 (40 μL) | 200 μL |
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| FLT3LG-ALDH16A1-20-REGR | 20 (40 μL) | 200 μL |
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| FLT3LG-ALDH16A1-20-REAQ | 20 (40 μL) | 200 μL |
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| FLT3LG-ALDH16A1-20-ORRE | 20 (40 μL) | 200 μL |
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| FLT3LG-ALDH16A1-20-OROR | 20 (40 μL) | 200 μL |
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| FLT3LG-ALDH16A1-20-ORGO | 20 (40 μL) | 200 μL |
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| FLT3LG-ALDH16A1-20-ORAQ | 20 (40 μL) | 200 μL |
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| FLT3LG-ALDH16A1-20-GORE | 20 (40 μL) | 200 μL |
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| FLT3LG-ALDH16A1-20-GOOR | 20 (40 μL) | 200 μL |
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| FLT3LG-ALDH16A1-20-GOGO | 20 (40 μL) | 200 μL |
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| FLT3LG-ALDH16A1-20-GOGR | 20 (40 μL) | 200 μL |
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| FLT3LG-ALDH16A1-20-GOAQ | 20 (40 μL) | 200 μL |
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| FLT3LG-ALDH16A1-20-GRRE | 20 (40 μL) | 200 μL |
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| FLT3LG-ALDH16A1-20-GROR | 20 (40 μL) | 200 μL |
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| FLT3LG-ALDH16A1-20-GRGO | 20 (40 μL) | 200 μL |
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| FLT3LG-ALDH16A1-20-GRGR | 20 (40 μL) | 200 μL |
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| FLT3LG-ALDH16A1-20-GRAQ | 20 (40 μL) | 200 μL |
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| FLT3LG-ALDH16A1-20-AQRE | 20 (40 μL) | 200 μL |
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| FLT3LG-ALDH16A1-20-AQOR | 20 (40 μL) | 200 μL |
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| FLT3LG-ALDH16A1-20-AQGO | 20 (40 μL) | 200 μL |
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| FLT3LG-ALDH16A1-20-AQGR | 20 (40 μL) | 200 μL |
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| FLT3LG-ALDH16A1-20-AQAQ | 20 (40 μL) | 200 μL |
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FLT3LG Gene Summary
Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 [PubMed 20933441]).[supplied by OMIM, Jan 2011]
Gene Name: Fms Related Tyrosine Kinase 3 Ligand
Chromosome: CHR19: 49977465 -49989488
Locus: 19q13.33
ALDH16A1 Gene Summary
This gene encodes a member of the aldehyde dehydrogenase superfamily. The family members act on aldehyde substrates and use nicotinamide adenine dinucleotide phosphate (NADP) as a cofactor. This gene is conserved in chimpanzee, dog, cow, mouse, rat, and zebrafish. The protein encoded by this gene interacts with maspardin, a protein that when truncated is responsible for Mast syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]
Gene Name: Aldehyde Dehydrogenase 16 Family Member A1
Chromosome: CHR19: 49956472 -49974305
Locus: 19q13.33
Gene Diseases
The FLT3LG ALDH16A1 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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