FLOT2-PEX12 Fusion FISH Probe
The FLOT2-PEX12 Fusion FISH Probe is used to confirm a fusion of the FLOT2 and PEX12 genes. The fusion of the FLOT2 and PEX12 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FLOT2-PEX12-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FLOT2-PEX12-20-RERE | 20 (40 μL) | 200 μL |
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| FLOT2-PEX12-20-REOR | 20 (40 μL) | 200 μL |
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| FLOT2-PEX12-20-REGO | 20 (40 μL) | 200 μL |
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| FLOT2-PEX12-20-REGR | 20 (40 μL) | 200 μL |
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| FLOT2-PEX12-20-REAQ | 20 (40 μL) | 200 μL |
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| FLOT2-PEX12-20-ORRE | 20 (40 μL) | 200 μL |
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| FLOT2-PEX12-20-OROR | 20 (40 μL) | 200 μL |
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| FLOT2-PEX12-20-ORGO | 20 (40 μL) | 200 μL |
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| FLOT2-PEX12-20-ORAQ | 20 (40 μL) | 200 μL |
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| FLOT2-PEX12-20-GORE | 20 (40 μL) | 200 μL |
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| FLOT2-PEX12-20-GOOR | 20 (40 μL) | 200 μL |
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| FLOT2-PEX12-20-GOGO | 20 (40 μL) | 200 μL |
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| FLOT2-PEX12-20-GOGR | 20 (40 μL) | 200 μL |
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| FLOT2-PEX12-20-GOAQ | 20 (40 μL) | 200 μL |
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| FLOT2-PEX12-20-GRRE | 20 (40 μL) | 200 μL |
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| FLOT2-PEX12-20-GROR | 20 (40 μL) | 200 μL |
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| FLOT2-PEX12-20-GRGO | 20 (40 μL) | 200 μL |
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| FLOT2-PEX12-20-GRGR | 20 (40 μL) | 200 μL |
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| FLOT2-PEX12-20-GRAQ | 20 (40 μL) | 200 μL |
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| FLOT2-PEX12-20-AQRE | 20 (40 μL) | 200 μL |
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| FLOT2-PEX12-20-AQOR | 20 (40 μL) | 200 μL |
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| FLOT2-PEX12-20-AQGO | 20 (40 μL) | 200 μL |
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| FLOT2-PEX12-20-AQGR | 20 (40 μL) | 200 μL |
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| FLOT2-PEX12-20-AQAQ | 20 (40 μL) | 200 μL |
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FLOT2 Gene Summary
Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal transduction. This gene encodes a caveolae-associated, integral membrane protein, which is thought to function in neuronal signaling. [provided by RefSeq, Jul 2008]
Gene Name: Flotillin 2
Chromosome: CHR17: 27206356 -27224715
Locus: 17q11.2
PEX12 Gene Summary
This gene belongs to the peroxin-12 family. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS). [provided by RefSeq, Oct 2008]
Gene Name: Peroxisomal Biogenesis Factor 12
Chromosome: CHR17: 33901813 -33905656
Locus: 17q12
Gene Diseases
The FLOT2 PEX12 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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