FLNA-EIF2AK2 Fusion FISH Probe
The FLNA-EIF2AK2 Fusion FISH Probe is used to confirm a fusion of the FLNA and EIF2AK2 genes. The fusion of the FLNA and EIF2AK2 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FLNA-EIF2AK2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FLNA-EIF2AK2-20-RERE | 20 (40 μL) | 200 μL |
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| FLNA-EIF2AK2-20-REOR | 20 (40 μL) | 200 μL |
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| FLNA-EIF2AK2-20-REGO | 20 (40 μL) | 200 μL |
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| FLNA-EIF2AK2-20-REGR | 20 (40 μL) | 200 μL |
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| FLNA-EIF2AK2-20-REAQ | 20 (40 μL) | 200 μL |
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| FLNA-EIF2AK2-20-ORRE | 20 (40 μL) | 200 μL |
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| FLNA-EIF2AK2-20-OROR | 20 (40 μL) | 200 μL |
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| FLNA-EIF2AK2-20-ORGO | 20 (40 μL) | 200 μL |
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| FLNA-EIF2AK2-20-ORAQ | 20 (40 μL) | 200 μL |
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| FLNA-EIF2AK2-20-GORE | 20 (40 μL) | 200 μL |
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| FLNA-EIF2AK2-20-GOOR | 20 (40 μL) | 200 μL |
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| FLNA-EIF2AK2-20-GOGO | 20 (40 μL) | 200 μL |
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| FLNA-EIF2AK2-20-GOGR | 20 (40 μL) | 200 μL |
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| FLNA-EIF2AK2-20-GOAQ | 20 (40 μL) | 200 μL |
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| FLNA-EIF2AK2-20-GRRE | 20 (40 μL) | 200 μL |
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| FLNA-EIF2AK2-20-GROR | 20 (40 μL) | 200 μL |
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| FLNA-EIF2AK2-20-GRGO | 20 (40 μL) | 200 μL |
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| FLNA-EIF2AK2-20-GRGR | 20 (40 μL) | 200 μL |
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| FLNA-EIF2AK2-20-GRAQ | 20 (40 μL) | 200 μL |
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| FLNA-EIF2AK2-20-AQRE | 20 (40 μL) | 200 μL |
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| FLNA-EIF2AK2-20-AQOR | 20 (40 μL) | 200 μL |
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| FLNA-EIF2AK2-20-AQGO | 20 (40 μL) | 200 μL |
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| FLNA-EIF2AK2-20-AQGR | 20 (40 μL) | 200 μL |
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| FLNA-EIF2AK2-20-AQAQ | 20 (40 μL) | 200 μL |
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FLNA Gene Summary
The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009]
Gene Name: Filamin A
Chromosome: CHRX: 153576899 -153603006
Locus: Xq28
EIF2AK2 Gene Summary
The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Gene Name: Eukaryotic Translation Initiation Factor 2 Alpha Kinase 2
Chromosome: CHR2: 37333698 -37384190
Locus: 2p22.2
Gene Diseases
The FLNA EIF2AK2 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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