FLCN-COPS3 Fusion FISH Probe
The FLCN-COPS3 Fusion FISH Probe is used to confirm a fusion of the FLCN and COPS3 genes. The fusion of the FLCN and COPS3 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FLCN-COPS3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| FLCN-COPS3-20-RERE | 20 (40 μL) | 200 μL |
|
|
| FLCN-COPS3-20-REOR | 20 (40 μL) | 200 μL |
|
|
| FLCN-COPS3-20-REGO | 20 (40 μL) | 200 μL |
|
|
| FLCN-COPS3-20-REGR | 20 (40 μL) | 200 μL |
|
|
| FLCN-COPS3-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| FLCN-COPS3-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| FLCN-COPS3-20-OROR | 20 (40 μL) | 200 μL |
|
|
| FLCN-COPS3-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| FLCN-COPS3-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| FLCN-COPS3-20-GORE | 20 (40 μL) | 200 μL |
|
|
| FLCN-COPS3-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| FLCN-COPS3-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| FLCN-COPS3-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| FLCN-COPS3-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| FLCN-COPS3-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| FLCN-COPS3-20-GROR | 20 (40 μL) | 200 μL |
|
|
| FLCN-COPS3-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| FLCN-COPS3-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| FLCN-COPS3-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| FLCN-COPS3-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| FLCN-COPS3-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| FLCN-COPS3-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| FLCN-COPS3-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| FLCN-COPS3-20-AQAQ | 20 (40 μL) | 200 μL |
|
COPS3 Gene Summary
The protein encoded by this gene possesses kinase activity that phosphorylates regulators involved in signal transduction. It phosphorylates I kappa-Balpha, p105, and c-Jun. It acts as a docking site for complex-mediated phosphorylation. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
Gene Name: COP9 Signalosome Subunit 3
Chromosome: CHR17: 17149937 -17184617
Locus: 17p11.2
FLCN Gene Summary
This gene is located within the Smith-Magenis syndrome region on chromosome 17. Mutations in this gene are associated with Birt-Hogg-Dube syndrome, which is characterized by fibrofolliculomas, renal tumors, lung cysts, and pneumothorax. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Folliculin
Chromosome: CHR17: 17115526 -17140502
Locus: 17p11.2
Gene Diseases
The FLCN COPS3 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|