FKTN-ULK4 Fusion FISH Probe
The FKTN-ULK4 Fusion FISH Probe is used to confirm a fusion of the FKTN and ULK4 genes. The fusion of the FKTN and ULK4 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FKTN-ULK4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FKTN-ULK4-20-RERE | 20 (40 μL) | 200 μL |
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| FKTN-ULK4-20-REOR | 20 (40 μL) | 200 μL |
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| FKTN-ULK4-20-REGO | 20 (40 μL) | 200 μL |
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| FKTN-ULK4-20-REGR | 20 (40 μL) | 200 μL |
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| FKTN-ULK4-20-REAQ | 20 (40 μL) | 200 μL |
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| FKTN-ULK4-20-ORRE | 20 (40 μL) | 200 μL |
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| FKTN-ULK4-20-OROR | 20 (40 μL) | 200 μL |
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| FKTN-ULK4-20-ORGO | 20 (40 μL) | 200 μL |
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| FKTN-ULK4-20-ORAQ | 20 (40 μL) | 200 μL |
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| FKTN-ULK4-20-GORE | 20 (40 μL) | 200 μL |
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| FKTN-ULK4-20-GOOR | 20 (40 μL) | 200 μL |
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| FKTN-ULK4-20-GOGO | 20 (40 μL) | 200 μL |
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| FKTN-ULK4-20-GOGR | 20 (40 μL) | 200 μL |
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| FKTN-ULK4-20-GOAQ | 20 (40 μL) | 200 μL |
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| FKTN-ULK4-20-GRRE | 20 (40 μL) | 200 μL |
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| FKTN-ULK4-20-GROR | 20 (40 μL) | 200 μL |
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| FKTN-ULK4-20-GRGO | 20 (40 μL) | 200 μL |
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| FKTN-ULK4-20-GRGR | 20 (40 μL) | 200 μL |
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| FKTN-ULK4-20-GRAQ | 20 (40 μL) | 200 μL |
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| FKTN-ULK4-20-AQRE | 20 (40 μL) | 200 μL |
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| FKTN-ULK4-20-AQOR | 20 (40 μL) | 200 μL |
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| FKTN-ULK4-20-AQGO | 20 (40 μL) | 200 μL |
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| FKTN-ULK4-20-AQGR | 20 (40 μL) | 200 μL |
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| FKTN-ULK4-20-AQAQ | 20 (40 μL) | 200 μL |
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FKTN Gene Summary
The protein encoded by this gene is a putative transmembrane protein that is localized to the cis-Golgi compartment, where it may be involved in the glycosylation of alpha-dystroglycan in skeletal muscle. The encoded protein is thought to be a glycosyltransferase and could play a role in brain development. Defects in this gene are a cause of Fukuyama-type congenital muscular dystrophy (FCMD), Walker-Warburg syndrome (WWS), limb-girdle muscular dystrophy type 2M (LGMD2M), and dilated cardiomyopathy type 1X (CMD1X). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2010]
Gene Name: Fukutin
Chromosome: CHR9: 108320410 -108403399
Locus: 9q31.2
ULK4 Gene Summary
This gene encodes a member of the unc-51-like serine/threonine kinase (STK) family. Members of this protein family play a role in neuronal growth and endocytosis. The encoded protein is likely involved in neurite branching, neurite elongation and neuronal migration. Genome-wide association studies (GWAS) indicate an association of variations in this gene with blood pressure and hypertension. Sequence variations in this gene may also be be associated with psychiatric disorders, including schizophrenia and bipolar disorder. Pseudogenes associated with this gene have been identified and are located on chromosome 15. [provided by RefSeq, Jul 2016]
Gene Name: Unc-51 Like Kinase 4
Chromosome: CHR3: 41288089 -42003660
Locus: 3p22.1
Gene Diseases
The FKTN ULK4 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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