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FHIT-KHDRBS3 Fusion FISH Probe

The FHIT-KHDRBS3 Fusion FISH Probe is used to confirm a fusion of the FHIT and KHDRBS3 genes. The fusion of the FHIT and KHDRBS3 genes has been associated with Lymphoid Neoplasm Diffuse Large B-cell Lymphoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
FHIT-KHDRBS3-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
FHIT-KHDRBS3-20-RERE 20 (40 μL) 200 μL
FHIT-KHDRBS3-20-REOR 20 (40 μL) 200 μL
FHIT-KHDRBS3-20-REGO 20 (40 μL) 200 μL
FHIT-KHDRBS3-20-REGR 20 (40 μL) 200 μL
FHIT-KHDRBS3-20-REAQ 20 (40 μL) 200 μL
FHIT-KHDRBS3-20-ORRE 20 (40 μL) 200 μL
FHIT-KHDRBS3-20-OROR 20 (40 μL) 200 μL
FHIT-KHDRBS3-20-ORGO 20 (40 μL) 200 μL
FHIT-KHDRBS3-20-ORAQ 20 (40 μL) 200 μL
FHIT-KHDRBS3-20-GORE 20 (40 μL) 200 μL
FHIT-KHDRBS3-20-GOOR 20 (40 μL) 200 μL
FHIT-KHDRBS3-20-GOGO 20 (40 μL) 200 μL
FHIT-KHDRBS3-20-GOGR 20 (40 μL) 200 μL
FHIT-KHDRBS3-20-GOAQ 20 (40 μL) 200 μL
FHIT-KHDRBS3-20-GRRE 20 (40 μL) 200 μL
FHIT-KHDRBS3-20-GROR 20 (40 μL) 200 μL
FHIT-KHDRBS3-20-GRGO 20 (40 μL) 200 μL
FHIT-KHDRBS3-20-GRGR 20 (40 μL) 200 μL
FHIT-KHDRBS3-20-GRAQ 20 (40 μL) 200 μL
FHIT-KHDRBS3-20-AQRE 20 (40 μL) 200 μL
FHIT-KHDRBS3-20-AQOR 20 (40 μL) 200 μL
FHIT-KHDRBS3-20-AQGO 20 (40 μL) 200 μL
FHIT-KHDRBS3-20-AQGR 20 (40 μL) 200 μL
FHIT-KHDRBS3-20-AQAQ 20 (40 μL) 200 μL

FHIT Gene Summary

The protein encoded by this gene is a P1-P3-bis(5'-adenosyl) triphosphate hydrolase involved in purine metabolism. This gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. The encoded protein is also a tumor suppressor, as loss of its activity results in replication stress and DNA damage. [provided by RefSeq, Aug 2017]

Gene Name: Fragile Histidine Triad

Chromosome: CHR3: 59735035 -61237133

Locus: 3p14.2

KHDRBS3 Gene Summary

The KH RNA Binding Domain Containing, Signal Transduction Associated 3 (KHDRBS3) gene is located on chr8 :136469715-136659848 at 8q24.23.

Gene Name: KH RNA Binding Domain Containing, Signal Transduction Associated 3

Chromosome: CHR8: 136469715 -136659848

Locus: 8q24.23

Gene Diseases

The FHIT KHDRBS3 Fusion has been associated with the following diseases:

Disease Name
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.