FGFR3-TPRG1 Fusion FISH Probe
The FGFR3-TPRG1 Fusion FISH Probe is used to confirm a fusion of the FGFR3 and TPRG1 genes. The fusion of the FGFR3 and TPRG1 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FGFR3-TPRG1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FGFR3-TPRG1-20-RERE | 20 (40 μL) | 200 μL |
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| FGFR3-TPRG1-20-REOR | 20 (40 μL) | 200 μL |
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| FGFR3-TPRG1-20-REGO | 20 (40 μL) | 200 μL |
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| FGFR3-TPRG1-20-REGR | 20 (40 μL) | 200 μL |
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| FGFR3-TPRG1-20-REAQ | 20 (40 μL) | 200 μL |
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| FGFR3-TPRG1-20-ORRE | 20 (40 μL) | 200 μL |
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| FGFR3-TPRG1-20-OROR | 20 (40 μL) | 200 μL |
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| FGFR3-TPRG1-20-ORGO | 20 (40 μL) | 200 μL |
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| FGFR3-TPRG1-20-ORAQ | 20 (40 μL) | 200 μL |
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| FGFR3-TPRG1-20-GORE | 20 (40 μL) | 200 μL |
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| FGFR3-TPRG1-20-GOOR | 20 (40 μL) | 200 μL |
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| FGFR3-TPRG1-20-GOGO | 20 (40 μL) | 200 μL |
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| FGFR3-TPRG1-20-GOGR | 20 (40 μL) | 200 μL |
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| FGFR3-TPRG1-20-GOAQ | 20 (40 μL) | 200 μL |
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| FGFR3-TPRG1-20-GRRE | 20 (40 μL) | 200 μL |
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| FGFR3-TPRG1-20-GROR | 20 (40 μL) | 200 μL |
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| FGFR3-TPRG1-20-GRGO | 20 (40 μL) | 200 μL |
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| FGFR3-TPRG1-20-GRGR | 20 (40 μL) | 200 μL |
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| FGFR3-TPRG1-20-GRAQ | 20 (40 μL) | 200 μL |
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| FGFR3-TPRG1-20-AQRE | 20 (40 μL) | 200 μL |
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| FGFR3-TPRG1-20-AQOR | 20 (40 μL) | 200 μL |
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| FGFR3-TPRG1-20-AQGO | 20 (40 μL) | 200 μL |
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| FGFR3-TPRG1-20-AQGR | 20 (40 μL) | 200 μL |
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| FGFR3-TPRG1-20-AQAQ | 20 (40 μL) | 200 μL |
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FGFR3 Gene Summary
This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia. [provided by RefSeq, Aug 2017]
Gene Name: Fibroblast Growth Factor Receptor 3
Chromosome: CHR4: 1795038 -1810599
Locus: 4p16.3
TPRG1 Gene Summary
The Tumor Protein P63 Regulated 1 (TPRG1) gene is located on chr3 :188889762-189041271 at 3q28.
Gene Name: Tumor Protein P63 Regulated 1
Chromosome: CHR3: 188889762 -189041271
Locus: 3q28
Gene Diseases
The FGFR3 TPRG1 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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