FGF13-DACH2 Fusion FISH Probe
The FGF13-DACH2 Fusion FISH Probe is used to confirm a fusion of the FGF13 and DACH2 genes. The fusion of the FGF13 and DACH2 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FGF13-DACH2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FGF13-DACH2-20-RERE | 20 (40 μL) | 200 μL |
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| FGF13-DACH2-20-REOR | 20 (40 μL) | 200 μL |
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| FGF13-DACH2-20-REGO | 20 (40 μL) | 200 μL |
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| FGF13-DACH2-20-REGR | 20 (40 μL) | 200 μL |
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| FGF13-DACH2-20-REAQ | 20 (40 μL) | 200 μL |
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| FGF13-DACH2-20-ORRE | 20 (40 μL) | 200 μL |
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| FGF13-DACH2-20-OROR | 20 (40 μL) | 200 μL |
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| FGF13-DACH2-20-ORGO | 20 (40 μL) | 200 μL |
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| FGF13-DACH2-20-ORAQ | 20 (40 μL) | 200 μL |
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| FGF13-DACH2-20-GORE | 20 (40 μL) | 200 μL |
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| FGF13-DACH2-20-GOOR | 20 (40 μL) | 200 μL |
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| FGF13-DACH2-20-GOGO | 20 (40 μL) | 200 μL |
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| FGF13-DACH2-20-GOGR | 20 (40 μL) | 200 μL |
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| FGF13-DACH2-20-GOAQ | 20 (40 μL) | 200 μL |
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| FGF13-DACH2-20-GRRE | 20 (40 μL) | 200 μL |
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| FGF13-DACH2-20-GROR | 20 (40 μL) | 200 μL |
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| FGF13-DACH2-20-GRGO | 20 (40 μL) | 200 μL |
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| FGF13-DACH2-20-GRGR | 20 (40 μL) | 200 μL |
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| FGF13-DACH2-20-GRAQ | 20 (40 μL) | 200 μL |
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| FGF13-DACH2-20-AQRE | 20 (40 μL) | 200 μL |
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| FGF13-DACH2-20-AQOR | 20 (40 μL) | 200 μL |
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| FGF13-DACH2-20-AQGO | 20 (40 μL) | 200 μL |
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| FGF13-DACH2-20-AQGR | 20 (40 μL) | 200 μL |
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| FGF13-DACH2-20-AQAQ | 20 (40 μL) | 200 μL |
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FGF13 Gene Summary
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This gene is located in a region on chromosome X, which is associated with Borjeson-Forssman-Lehmann syndrome (BFLS), making it a possible candidate gene for familial cases of the BFLS, and for other syndromal and nonspecific forms of X-linked cognitive disability mapping to this region. Alternative splicing of this gene at the 5' end results in several transcript variants encoding different isoforms with different N-termini. [provided by RefSeq, Nov 2008]
Gene Name: Fibroblast Growth Factor 13
Chromosome: CHRX: 137713733 -138287185
Locus: Xq26.3-q27.1
DACH2 Gene Summary
This gene is one of two genes which encode a protein similar to the Drosophila protein dachshund, a transcription factor involved in cell fate determination in the eye, limb and genital disc of the fly. The encoded protein contains two characteristic dachshund domains: an N-terminal domain responsible for DNA binding and a C-terminal domain responsible for protein-protein interactions. This gene is located on the X chromosome and is subject to inactivation by DNA methylation. The encoded protein may be involved in regulation of organogenesis and myogenesis, and may play a role in premature ovarian failure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]
Gene Name: Dachshund Family Transcription Factor 2
Chromosome: CHRX: 85403454 -86087605
Locus: Xq21.2
Gene Diseases
The FGF13 DACH2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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