FGF12-LRRC15 Fusion FISH Probe
The FGF12-LRRC15 Fusion FISH Probe is used to confirm a fusion of the FGF12 and LRRC15 genes. The fusion of the FGF12 and LRRC15 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FGF12-LRRC15-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FGF12-LRRC15-20-RERE | 20 (40 μL) | 200 μL |
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| FGF12-LRRC15-20-REOR | 20 (40 μL) | 200 μL |
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| FGF12-LRRC15-20-REGO | 20 (40 μL) | 200 μL |
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| FGF12-LRRC15-20-REGR | 20 (40 μL) | 200 μL |
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| FGF12-LRRC15-20-REAQ | 20 (40 μL) | 200 μL |
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| FGF12-LRRC15-20-ORRE | 20 (40 μL) | 200 μL |
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| FGF12-LRRC15-20-OROR | 20 (40 μL) | 200 μL |
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| FGF12-LRRC15-20-ORGO | 20 (40 μL) | 200 μL |
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| FGF12-LRRC15-20-ORAQ | 20 (40 μL) | 200 μL |
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| FGF12-LRRC15-20-GORE | 20 (40 μL) | 200 μL |
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| FGF12-LRRC15-20-GOOR | 20 (40 μL) | 200 μL |
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| FGF12-LRRC15-20-GOGO | 20 (40 μL) | 200 μL |
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| FGF12-LRRC15-20-GOGR | 20 (40 μL) | 200 μL |
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| FGF12-LRRC15-20-GOAQ | 20 (40 μL) | 200 μL |
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| FGF12-LRRC15-20-GRRE | 20 (40 μL) | 200 μL |
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| FGF12-LRRC15-20-GROR | 20 (40 μL) | 200 μL |
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| FGF12-LRRC15-20-GRGO | 20 (40 μL) | 200 μL |
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| FGF12-LRRC15-20-GRGR | 20 (40 μL) | 200 μL |
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| FGF12-LRRC15-20-GRAQ | 20 (40 μL) | 200 μL |
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| FGF12-LRRC15-20-AQRE | 20 (40 μL) | 200 μL |
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| FGF12-LRRC15-20-AQOR | 20 (40 μL) | 200 μL |
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| FGF12-LRRC15-20-AQGO | 20 (40 μL) | 200 μL |
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| FGF12-LRRC15-20-AQGR | 20 (40 μL) | 200 μL |
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| FGF12-LRRC15-20-AQAQ | 20 (40 μL) | 200 μL |
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FGF12 Gene Summary
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This growth factor lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfected into mammalian cells, this protein accumulated in the nucleus, but was not secreted. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Gene Name: Fibroblast Growth Factor 12
Chromosome: CHR3: 191857181 -192445388
Locus: 3q28-q29
LRRC15 Gene Summary
The Leucine Rich Repeat Containing 15 (LRRC15) gene is located on chr3 :194075975-194090472 at 3q29.
Gene Name: Leucine Rich Repeat Containing 15
Chromosome: CHR3: 194075975 -194090472
Locus: 3q29
Gene Diseases
The FGF12 LRRC15 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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