FGD6-VEZT Fusion FISH Probe
The FGD6-VEZT Fusion FISH Probe is used to confirm a fusion of the FGD6 and VEZT genes. The fusion of the FGD6 and VEZT genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FGD6-VEZT-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FGD6-VEZT-20-RERE | 20 (40 μL) | 200 μL |
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| FGD6-VEZT-20-REOR | 20 (40 μL) | 200 μL |
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| FGD6-VEZT-20-REGO | 20 (40 μL) | 200 μL |
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| FGD6-VEZT-20-REGR | 20 (40 μL) | 200 μL |
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| FGD6-VEZT-20-REAQ | 20 (40 μL) | 200 μL |
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| FGD6-VEZT-20-ORRE | 20 (40 μL) | 200 μL |
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| FGD6-VEZT-20-OROR | 20 (40 μL) | 200 μL |
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| FGD6-VEZT-20-ORGO | 20 (40 μL) | 200 μL |
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| FGD6-VEZT-20-ORAQ | 20 (40 μL) | 200 μL |
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| FGD6-VEZT-20-GORE | 20 (40 μL) | 200 μL |
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| FGD6-VEZT-20-GOOR | 20 (40 μL) | 200 μL |
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| FGD6-VEZT-20-GOGO | 20 (40 μL) | 200 μL |
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| FGD6-VEZT-20-GOGR | 20 (40 μL) | 200 μL |
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| FGD6-VEZT-20-GOAQ | 20 (40 μL) | 200 μL |
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| FGD6-VEZT-20-GRRE | 20 (40 μL) | 200 μL |
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| FGD6-VEZT-20-GROR | 20 (40 μL) | 200 μL |
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| FGD6-VEZT-20-GRGO | 20 (40 μL) | 200 μL |
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| FGD6-VEZT-20-GRGR | 20 (40 μL) | 200 μL |
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| FGD6-VEZT-20-GRAQ | 20 (40 μL) | 200 μL |
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| FGD6-VEZT-20-AQRE | 20 (40 μL) | 200 μL |
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| FGD6-VEZT-20-AQOR | 20 (40 μL) | 200 μL |
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| FGD6-VEZT-20-AQGO | 20 (40 μL) | 200 μL |
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| FGD6-VEZT-20-AQGR | 20 (40 μL) | 200 μL |
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| FGD6-VEZT-20-AQAQ | 20 (40 μL) | 200 μL |
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VEZT Gene Summary
This gene encodes a transmembrane protein which has been localized to adherens junctions and shown to bind to myosin VIIA. Examination of expression of this gene in gastric cancer tissues have shown that expression is decreased which appears to be related to hypermethylation of the promoter. Expression of this gene may also be inhibited by binding of a specific microRNA to a target sequence in the 3' UTR of the transcripts. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2011]
Gene Name: Vezatin, Adherens Junctions Transmembrane Protein
Chromosome: CHR12: 95611521 -95696566
Locus: 12q22
FGD6 Gene Summary
The FYVE, RhoGEF And PH Domain Containing 6 (FGD6) gene is located on chr12 :95470524-95611240 at 12q22.
Gene Name: FYVE, RhoGEF And PH Domain Containing 6
Chromosome: CHR12: 95470524 -95611240
Locus: 12q22
Gene Diseases
The FGD6 VEZT Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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