FGD4-CNTN5 Fusion FISH Probe
The FGD4-CNTN5 Fusion FISH Probe is used to confirm a fusion of the FGD4 and CNTN5 genes. The fusion of the FGD4 and CNTN5 genes has been associated with Rectum Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FGD4-CNTN5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FGD4-CNTN5-20-RERE | 20 (40 μL) | 200 μL |
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| FGD4-CNTN5-20-REOR | 20 (40 μL) | 200 μL |
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| FGD4-CNTN5-20-REGO | 20 (40 μL) | 200 μL |
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| FGD4-CNTN5-20-REGR | 20 (40 μL) | 200 μL |
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| FGD4-CNTN5-20-REAQ | 20 (40 μL) | 200 μL |
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| FGD4-CNTN5-20-ORRE | 20 (40 μL) | 200 μL |
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| FGD4-CNTN5-20-OROR | 20 (40 μL) | 200 μL |
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| FGD4-CNTN5-20-ORGO | 20 (40 μL) | 200 μL |
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| FGD4-CNTN5-20-ORAQ | 20 (40 μL) | 200 μL |
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| FGD4-CNTN5-20-GORE | 20 (40 μL) | 200 μL |
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| FGD4-CNTN5-20-GOOR | 20 (40 μL) | 200 μL |
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| FGD4-CNTN5-20-GOGO | 20 (40 μL) | 200 μL |
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| FGD4-CNTN5-20-GOGR | 20 (40 μL) | 200 μL |
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| FGD4-CNTN5-20-GOAQ | 20 (40 μL) | 200 μL |
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| FGD4-CNTN5-20-GRRE | 20 (40 μL) | 200 μL |
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| FGD4-CNTN5-20-GROR | 20 (40 μL) | 200 μL |
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| FGD4-CNTN5-20-GRGO | 20 (40 μL) | 200 μL |
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| FGD4-CNTN5-20-GRGR | 20 (40 μL) | 200 μL |
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| FGD4-CNTN5-20-GRAQ | 20 (40 μL) | 200 μL |
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| FGD4-CNTN5-20-AQRE | 20 (40 μL) | 200 μL |
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| FGD4-CNTN5-20-AQOR | 20 (40 μL) | 200 μL |
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| FGD4-CNTN5-20-AQGO | 20 (40 μL) | 200 μL |
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| FGD4-CNTN5-20-AQGR | 20 (40 μL) | 200 μL |
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| FGD4-CNTN5-20-AQAQ | 20 (40 μL) | 200 μL |
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CNTN5 Gene Summary
The protein encoded by this gene is a member of the immunoglobulin superfamily, and contactin family, which mediate cell surface interactions during nervous system development. This protein is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
Gene Name: Contactin 5
Chromosome: CHR11: 98891705 -100229616
Locus: 11q22.1
FGD4 Gene Summary
This gene encodes a protein that is involved in the regulation of the actin cytoskeleton and cell shape. This protein contains an actin filament-binding domain, which together with its Dbl homology domain and one of its pleckstrin homology domains, can form microspikes. This protein can activate MAPK8 independently of the actin filament-binding domain, and it is also involved in the activation of CDC42 via the exchange of bound GDP for free GTP. The activation of CDC42 also enables this protein to play a role in mediating the cellular invasion of Cryptosporidium parvum, an intracellular parasite that infects the gastrointestinal tract. Mutations in this gene can cause Charcot-Marie-Tooth disease type 4H (CMT4H), a disorder of the peripheral nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015]
Gene Name: FYVE, RhoGEF And PH Domain Containing 4
Chromosome: CHR12: 32655040 -32798984
Locus: 12p11.21
Gene Diseases
The FGD4 CNTN5 Fusion has been associated with the following diseases:
| Disease Name |
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| Rectum Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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