FGB-PLEKHA5 Fusion FISH Probe
The FGB-PLEKHA5 Fusion FISH Probe is used to confirm a fusion of the FGB and PLEKHA5 genes. The fusion of the FGB and PLEKHA5 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FGB-PLEKHA5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FGB-PLEKHA5-20-RERE | 20 (40 μL) | 200 μL |
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| FGB-PLEKHA5-20-REOR | 20 (40 μL) | 200 μL |
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| FGB-PLEKHA5-20-REGO | 20 (40 μL) | 200 μL |
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| FGB-PLEKHA5-20-REGR | 20 (40 μL) | 200 μL |
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| FGB-PLEKHA5-20-REAQ | 20 (40 μL) | 200 μL |
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| FGB-PLEKHA5-20-ORRE | 20 (40 μL) | 200 μL |
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| FGB-PLEKHA5-20-OROR | 20 (40 μL) | 200 μL |
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| FGB-PLEKHA5-20-ORGO | 20 (40 μL) | 200 μL |
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| FGB-PLEKHA5-20-ORAQ | 20 (40 μL) | 200 μL |
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| FGB-PLEKHA5-20-GORE | 20 (40 μL) | 200 μL |
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| FGB-PLEKHA5-20-GOOR | 20 (40 μL) | 200 μL |
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| FGB-PLEKHA5-20-GOGO | 20 (40 μL) | 200 μL |
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| FGB-PLEKHA5-20-GOGR | 20 (40 μL) | 200 μL |
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| FGB-PLEKHA5-20-GOAQ | 20 (40 μL) | 200 μL |
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| FGB-PLEKHA5-20-GRRE | 20 (40 μL) | 200 μL |
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| FGB-PLEKHA5-20-GROR | 20 (40 μL) | 200 μL |
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| FGB-PLEKHA5-20-GRGO | 20 (40 μL) | 200 μL |
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| FGB-PLEKHA5-20-GRGR | 20 (40 μL) | 200 μL |
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| FGB-PLEKHA5-20-GRAQ | 20 (40 μL) | 200 μL |
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| FGB-PLEKHA5-20-AQRE | 20 (40 μL) | 200 μL |
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| FGB-PLEKHA5-20-AQOR | 20 (40 μL) | 200 μL |
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| FGB-PLEKHA5-20-AQGO | 20 (40 μL) | 200 μL |
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| FGB-PLEKHA5-20-AQGR | 20 (40 μL) | 200 μL |
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| FGB-PLEKHA5-20-AQAQ | 20 (40 μL) | 200 μL |
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FGB Gene Summary
The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]
Gene Name: Fibrinogen Beta Chain
Chromosome: CHR4: 155484131 -155493915
Locus: 4q31.3
PLEKHA5 Gene Summary
The Pleckstrin Homology Domain Containing A5 (PLEKHA5) gene is located on chr12 :19282625-19529333 at 12p12.3.
Gene Name: Pleckstrin Homology Domain Containing A5
Chromosome: CHR12: 19282625 -19529333
Locus: 12p12.3
Gene Diseases
The FGB PLEKHA5 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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