FEZ2-RAB10 Fusion FISH Probe
The FEZ2-RAB10 Fusion FISH Probe is used to confirm a fusion of the FEZ2 and RAB10 genes. The fusion of the FEZ2 and RAB10 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FEZ2-RAB10-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FEZ2-RAB10-20-RERE | 20 (40 μL) | 200 μL |
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| FEZ2-RAB10-20-REOR | 20 (40 μL) | 200 μL |
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| FEZ2-RAB10-20-REGO | 20 (40 μL) | 200 μL |
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| FEZ2-RAB10-20-REGR | 20 (40 μL) | 200 μL |
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| FEZ2-RAB10-20-REAQ | 20 (40 μL) | 200 μL |
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| FEZ2-RAB10-20-ORRE | 20 (40 μL) | 200 μL |
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| FEZ2-RAB10-20-OROR | 20 (40 μL) | 200 μL |
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| FEZ2-RAB10-20-ORGO | 20 (40 μL) | 200 μL |
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| FEZ2-RAB10-20-ORAQ | 20 (40 μL) | 200 μL |
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| FEZ2-RAB10-20-GORE | 20 (40 μL) | 200 μL |
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| FEZ2-RAB10-20-GOOR | 20 (40 μL) | 200 μL |
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| FEZ2-RAB10-20-GOGO | 20 (40 μL) | 200 μL |
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| FEZ2-RAB10-20-GOGR | 20 (40 μL) | 200 μL |
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| FEZ2-RAB10-20-GOAQ | 20 (40 μL) | 200 μL |
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| FEZ2-RAB10-20-GRRE | 20 (40 μL) | 200 μL |
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| FEZ2-RAB10-20-GROR | 20 (40 μL) | 200 μL |
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| FEZ2-RAB10-20-GRGO | 20 (40 μL) | 200 μL |
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| FEZ2-RAB10-20-GRGR | 20 (40 μL) | 200 μL |
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| FEZ2-RAB10-20-GRAQ | 20 (40 μL) | 200 μL |
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| FEZ2-RAB10-20-AQRE | 20 (40 μL) | 200 μL |
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| FEZ2-RAB10-20-AQOR | 20 (40 μL) | 200 μL |
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| FEZ2-RAB10-20-AQGO | 20 (40 μL) | 200 μL |
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| FEZ2-RAB10-20-AQGR | 20 (40 μL) | 200 μL |
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| FEZ2-RAB10-20-AQAQ | 20 (40 μL) | 200 μL |
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FEZ2 Gene Summary
This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Other orthologs include the rat gene that encodes zygin II, which can bind to synaptotagmin. [provided by RefSeq, Jul 2008]
Gene Name: Fasciculation And Elongation Protein Zeta 2
Chromosome: CHR2: 36779403 -36825332
Locus: 2p22.2
RAB10 Gene Summary
RAB10 belongs to the RAS (see HRAS; MIM 190020) superfamily of small GTPases. RAB proteins localize to exocytic and endocytic compartments and regulate intracellular vesicle trafficking (Bao et al., 1998 [PubMed 9918381]).[supplied by OMIM, Mar 2009]
Gene Name: RAB10, Member RAS Oncogene Family
Chromosome: CHR2: 26256728 -26360323
Locus: 2p23.3
Gene Diseases
The FEZ2 RAB10 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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