FDPS-IPO9 Fusion FISH Probe
The FDPS-IPO9 Fusion FISH Probe is used to confirm a fusion of the FDPS and IPO9 genes. The fusion of the FDPS and IPO9 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FDPS-IPO9-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FDPS-IPO9-20-RERE | 20 (40 μL) | 200 μL |
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| FDPS-IPO9-20-REOR | 20 (40 μL) | 200 μL |
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| FDPS-IPO9-20-REGO | 20 (40 μL) | 200 μL |
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| FDPS-IPO9-20-REGR | 20 (40 μL) | 200 μL |
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| FDPS-IPO9-20-REAQ | 20 (40 μL) | 200 μL |
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| FDPS-IPO9-20-ORRE | 20 (40 μL) | 200 μL |
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| FDPS-IPO9-20-OROR | 20 (40 μL) | 200 μL |
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| FDPS-IPO9-20-ORGO | 20 (40 μL) | 200 μL |
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| FDPS-IPO9-20-ORAQ | 20 (40 μL) | 200 μL |
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| FDPS-IPO9-20-GORE | 20 (40 μL) | 200 μL |
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| FDPS-IPO9-20-GOOR | 20 (40 μL) | 200 μL |
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| FDPS-IPO9-20-GOGO | 20 (40 μL) | 200 μL |
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| FDPS-IPO9-20-GOGR | 20 (40 μL) | 200 μL |
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| FDPS-IPO9-20-GOAQ | 20 (40 μL) | 200 μL |
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| FDPS-IPO9-20-GRRE | 20 (40 μL) | 200 μL |
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| FDPS-IPO9-20-GROR | 20 (40 μL) | 200 μL |
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| FDPS-IPO9-20-GRGO | 20 (40 μL) | 200 μL |
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| FDPS-IPO9-20-GRGR | 20 (40 μL) | 200 μL |
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| FDPS-IPO9-20-GRAQ | 20 (40 μL) | 200 μL |
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| FDPS-IPO9-20-AQRE | 20 (40 μL) | 200 μL |
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| FDPS-IPO9-20-AQOR | 20 (40 μL) | 200 μL |
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| FDPS-IPO9-20-AQGO | 20 (40 μL) | 200 μL |
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| FDPS-IPO9-20-AQGR | 20 (40 μL) | 200 μL |
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| FDPS-IPO9-20-AQAQ | 20 (40 μL) | 200 μL |
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FDPS Gene Summary
This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2008]
Gene Name: Farnesyl Diphosphate Synthase
Chromosome: CHR1: 155278538 -155290457
Locus: 1q22
IPO9 Gene Summary
The Importin 9 (IPO9) gene is located on chr1 :201798287-201853422 at 1q32.1.
Gene Name: Importin 9
Chromosome: CHR1: 201798287 -201853422
Locus: 1q32.1
Gene Diseases
The FDPS IPO9 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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