FDFT1-GATA4 Fusion FISH Probe
The FDFT1-GATA4 Fusion FISH Probe is used to confirm a fusion of the FDFT1 and GATA4 genes. The fusion of the FDFT1 and GATA4 genes has been associated with Ovarian Serous Cystadenocarcinoma, and Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FDFT1-GATA4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FDFT1-GATA4-20-RERE | 20 (40 μL) | 200 μL |
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| FDFT1-GATA4-20-REOR | 20 (40 μL) | 200 μL |
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| FDFT1-GATA4-20-REGO | 20 (40 μL) | 200 μL |
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| FDFT1-GATA4-20-REGR | 20 (40 μL) | 200 μL |
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| FDFT1-GATA4-20-REAQ | 20 (40 μL) | 200 μL |
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| FDFT1-GATA4-20-ORRE | 20 (40 μL) | 200 μL |
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| FDFT1-GATA4-20-OROR | 20 (40 μL) | 200 μL |
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| FDFT1-GATA4-20-ORGO | 20 (40 μL) | 200 μL |
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| FDFT1-GATA4-20-ORAQ | 20 (40 μL) | 200 μL |
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| FDFT1-GATA4-20-GORE | 20 (40 μL) | 200 μL |
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| FDFT1-GATA4-20-GOOR | 20 (40 μL) | 200 μL |
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| FDFT1-GATA4-20-GOGO | 20 (40 μL) | 200 μL |
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| FDFT1-GATA4-20-GOGR | 20 (40 μL) | 200 μL |
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| FDFT1-GATA4-20-GOAQ | 20 (40 μL) | 200 μL |
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| FDFT1-GATA4-20-GRRE | 20 (40 μL) | 200 μL |
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| FDFT1-GATA4-20-GROR | 20 (40 μL) | 200 μL |
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| FDFT1-GATA4-20-GRGO | 20 (40 μL) | 200 μL |
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| FDFT1-GATA4-20-GRGR | 20 (40 μL) | 200 μL |
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| FDFT1-GATA4-20-GRAQ | 20 (40 μL) | 200 μL |
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| FDFT1-GATA4-20-AQRE | 20 (40 μL) | 200 μL |
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| FDFT1-GATA4-20-AQOR | 20 (40 μL) | 200 μL |
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| FDFT1-GATA4-20-AQGO | 20 (40 μL) | 200 μL |
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| FDFT1-GATA4-20-AQGR | 20 (40 μL) | 200 μL |
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| FDFT1-GATA4-20-AQAQ | 20 (40 μL) | 200 μL |
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FDFT1 Gene Summary
This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. [provided by RefSeq, Jul 2008]
Gene Name: Farnesyl-diphosphate Farnesyltransferase 1
Chromosome: CHR8: 11660189 -11696818
Locus: 8p23.1
GATA4 Gene Summary
This gene encodes a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function, and is necessary for normal testicular development. Mutations in this gene have been associated with cardiac septal defects. Additionally, alterations in gene expression have been associated with several cancer types. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Gene Name: GATA Binding Protein 4
Chromosome: CHR8: 11561716 -11617509
Locus: 8p23.1
Gene Diseases
The FDFT1 GATA4 Fusion has been associated with the following diseases:
| Disease Name |
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| Ovarian Serous Cystadenocarcinoma |
| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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