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FCHSD2-PPFIA1 Fusion FISH Probe

The FCHSD2-PPFIA1 Fusion FISH Probe is used to confirm a fusion of the FCHSD2 and PPFIA1 genes. The fusion of the FCHSD2 and PPFIA1 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
FCHSD2-PPFIA1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
FCHSD2-PPFIA1-20-RERE 20 (40 μL) 200 μL
FCHSD2-PPFIA1-20-REOR 20 (40 μL) 200 μL
FCHSD2-PPFIA1-20-REGO 20 (40 μL) 200 μL
FCHSD2-PPFIA1-20-REGR 20 (40 μL) 200 μL
FCHSD2-PPFIA1-20-REAQ 20 (40 μL) 200 μL
FCHSD2-PPFIA1-20-ORRE 20 (40 μL) 200 μL
FCHSD2-PPFIA1-20-OROR 20 (40 μL) 200 μL
FCHSD2-PPFIA1-20-ORGO 20 (40 μL) 200 μL
FCHSD2-PPFIA1-20-ORAQ 20 (40 μL) 200 μL
FCHSD2-PPFIA1-20-GORE 20 (40 μL) 200 μL
FCHSD2-PPFIA1-20-GOOR 20 (40 μL) 200 μL
FCHSD2-PPFIA1-20-GOGO 20 (40 μL) 200 μL
FCHSD2-PPFIA1-20-GOGR 20 (40 μL) 200 μL
FCHSD2-PPFIA1-20-GOAQ 20 (40 μL) 200 μL
FCHSD2-PPFIA1-20-GRRE 20 (40 μL) 200 μL
FCHSD2-PPFIA1-20-GROR 20 (40 μL) 200 μL
FCHSD2-PPFIA1-20-GRGO 20 (40 μL) 200 μL
FCHSD2-PPFIA1-20-GRGR 20 (40 μL) 200 μL
FCHSD2-PPFIA1-20-GRAQ 20 (40 μL) 200 μL
FCHSD2-PPFIA1-20-AQRE 20 (40 μL) 200 μL
FCHSD2-PPFIA1-20-AQOR 20 (40 μL) 200 μL
FCHSD2-PPFIA1-20-AQGO 20 (40 μL) 200 μL
FCHSD2-PPFIA1-20-AQGR 20 (40 μL) 200 μL
FCHSD2-PPFIA1-20-AQAQ 20 (40 μL) 200 μL

PPFIA1 Gene Summary

The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

Gene Name: PTPRF Interacting Protein Alpha 1

Chromosome: CHR11: 70116822 -70230502

Locus: 11q13.3

FCHSD2 Gene Summary

The FCH And Double SH3 Domains 2 (FCHSD2) gene is located on chr11 :72547789-72853143 at 11q13.4.

Gene Name: FCH And Double SH3 Domains 2

Chromosome: CHR11: 72547789 -72853143

Locus: 11q13.4

Gene Diseases

The FCHSD2 PPFIA1 Fusion has been associated with the following diseases:

Disease Name
Bladder Urothelial Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.