FBXW11-RBM11 Fusion FISH Probe
The FBXW11-RBM11 Fusion FISH Probe is used to confirm a fusion of the FBXW11 and RBM11 genes. The fusion of the FBXW11 and RBM11 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FBXW11-RBM11-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FBXW11-RBM11-20-RERE | 20 (40 μL) | 200 μL |
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| FBXW11-RBM11-20-REOR | 20 (40 μL) | 200 μL |
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| FBXW11-RBM11-20-REGO | 20 (40 μL) | 200 μL |
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| FBXW11-RBM11-20-REGR | 20 (40 μL) | 200 μL |
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| FBXW11-RBM11-20-REAQ | 20 (40 μL) | 200 μL |
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| FBXW11-RBM11-20-ORRE | 20 (40 μL) | 200 μL |
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| FBXW11-RBM11-20-OROR | 20 (40 μL) | 200 μL |
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| FBXW11-RBM11-20-ORGO | 20 (40 μL) | 200 μL |
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| FBXW11-RBM11-20-ORAQ | 20 (40 μL) | 200 μL |
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| FBXW11-RBM11-20-GORE | 20 (40 μL) | 200 μL |
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| FBXW11-RBM11-20-GOOR | 20 (40 μL) | 200 μL |
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| FBXW11-RBM11-20-GOGO | 20 (40 μL) | 200 μL |
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| FBXW11-RBM11-20-GOGR | 20 (40 μL) | 200 μL |
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| FBXW11-RBM11-20-GOAQ | 20 (40 μL) | 200 μL |
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| FBXW11-RBM11-20-GRRE | 20 (40 μL) | 200 μL |
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| FBXW11-RBM11-20-GROR | 20 (40 μL) | 200 μL |
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| FBXW11-RBM11-20-GRGO | 20 (40 μL) | 200 μL |
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| FBXW11-RBM11-20-GRGR | 20 (40 μL) | 200 μL |
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| FBXW11-RBM11-20-GRAQ | 20 (40 μL) | 200 μL |
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| FBXW11-RBM11-20-AQRE | 20 (40 μL) | 200 μL |
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| FBXW11-RBM11-20-AQOR | 20 (40 μL) | 200 μL |
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| FBXW11-RBM11-20-AQGO | 20 (40 μL) | 200 μL |
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| FBXW11-RBM11-20-AQGR | 20 (40 μL) | 200 μL |
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| FBXW11-RBM11-20-AQAQ | 20 (40 μL) | 200 μL |
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FBXW11 Gene Summary
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons. [provided by RefSeq, Jul 2008]
Gene Name: F-box And WD Repeat Domain Containing 11
Chromosome: CHR5: 171288555 -171433877
Locus: 5q35.1
RBM11 Gene Summary
The RNA Binding Motif Protein 11 (RBM11) gene is located on chr21 :15588465-15600693 at 21q11.2.
Gene Name: RNA Binding Motif Protein 11
Chromosome: CHR21: 15588465 -15600693
Locus: 21q11.2
Gene Diseases
The FBXW11 RBM11 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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