FBXW11-NUP210L Fusion FISH Probe
The FBXW11-NUP210L Fusion FISH Probe is used to confirm a fusion of the FBXW11 and NUP210L genes. The fusion of the FBXW11 and NUP210L genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FBXW11-NUP210L-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FBXW11-NUP210L-20-RERE | 20 (40 μL) | 200 μL |
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| FBXW11-NUP210L-20-REOR | 20 (40 μL) | 200 μL |
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| FBXW11-NUP210L-20-REGO | 20 (40 μL) | 200 μL |
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| FBXW11-NUP210L-20-REGR | 20 (40 μL) | 200 μL |
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| FBXW11-NUP210L-20-REAQ | 20 (40 μL) | 200 μL |
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| FBXW11-NUP210L-20-ORRE | 20 (40 μL) | 200 μL |
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| FBXW11-NUP210L-20-OROR | 20 (40 μL) | 200 μL |
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| FBXW11-NUP210L-20-ORGO | 20 (40 μL) | 200 μL |
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| FBXW11-NUP210L-20-ORAQ | 20 (40 μL) | 200 μL |
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| FBXW11-NUP210L-20-GORE | 20 (40 μL) | 200 μL |
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| FBXW11-NUP210L-20-GOOR | 20 (40 μL) | 200 μL |
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| FBXW11-NUP210L-20-GOGO | 20 (40 μL) | 200 μL |
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| FBXW11-NUP210L-20-GOGR | 20 (40 μL) | 200 μL |
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| FBXW11-NUP210L-20-GOAQ | 20 (40 μL) | 200 μL |
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| FBXW11-NUP210L-20-GRRE | 20 (40 μL) | 200 μL |
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| FBXW11-NUP210L-20-GROR | 20 (40 μL) | 200 μL |
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| FBXW11-NUP210L-20-GRGO | 20 (40 μL) | 200 μL |
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| FBXW11-NUP210L-20-GRGR | 20 (40 μL) | 200 μL |
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| FBXW11-NUP210L-20-GRAQ | 20 (40 μL) | 200 μL |
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| FBXW11-NUP210L-20-AQRE | 20 (40 μL) | 200 μL |
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| FBXW11-NUP210L-20-AQOR | 20 (40 μL) | 200 μL |
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| FBXW11-NUP210L-20-AQGO | 20 (40 μL) | 200 μL |
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| FBXW11-NUP210L-20-AQGR | 20 (40 μL) | 200 μL |
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| FBXW11-NUP210L-20-AQAQ | 20 (40 μL) | 200 μL |
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FBXW11 Gene Summary
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons. [provided by RefSeq, Jul 2008]
Gene Name: F-box And WD Repeat Domain Containing 11
Chromosome: CHR5: 171288555 -171433877
Locus: 5q35.1
NUP210L Gene Summary
The Nucleoporin 210 Like (NUP210L) gene is located on chr1 :153965167-154127592 at 1q21.3.
Gene Name: Nucleoporin 210 Like
Chromosome: CHR1: 153965167 -154127592
Locus: 1q21.3
Gene Diseases
The FBXW11 NUP210L Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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