FBXO42-SPATA21 Fusion FISH Probe
The FBXO42-SPATA21 Fusion FISH Probe is used to confirm a fusion of the FBXO42 and SPATA21 genes. The fusion of the FBXO42 and SPATA21 genes has been associated with Bladder Urothelial Carcinoma, and Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FBXO42-SPATA21-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FBXO42-SPATA21-20-RERE | 20 (40 μL) | 200 μL |
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| FBXO42-SPATA21-20-REOR | 20 (40 μL) | 200 μL |
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| FBXO42-SPATA21-20-REGO | 20 (40 μL) | 200 μL |
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| FBXO42-SPATA21-20-REGR | 20 (40 μL) | 200 μL |
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| FBXO42-SPATA21-20-REAQ | 20 (40 μL) | 200 μL |
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| FBXO42-SPATA21-20-ORRE | 20 (40 μL) | 200 μL |
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| FBXO42-SPATA21-20-OROR | 20 (40 μL) | 200 μL |
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| FBXO42-SPATA21-20-ORGO | 20 (40 μL) | 200 μL |
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| FBXO42-SPATA21-20-ORAQ | 20 (40 μL) | 200 μL |
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| FBXO42-SPATA21-20-GORE | 20 (40 μL) | 200 μL |
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| FBXO42-SPATA21-20-GOOR | 20 (40 μL) | 200 μL |
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| FBXO42-SPATA21-20-GOGO | 20 (40 μL) | 200 μL |
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| FBXO42-SPATA21-20-GOGR | 20 (40 μL) | 200 μL |
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| FBXO42-SPATA21-20-GOAQ | 20 (40 μL) | 200 μL |
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| FBXO42-SPATA21-20-GRRE | 20 (40 μL) | 200 μL |
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| FBXO42-SPATA21-20-GROR | 20 (40 μL) | 200 μL |
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| FBXO42-SPATA21-20-GRGO | 20 (40 μL) | 200 μL |
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| FBXO42-SPATA21-20-GRGR | 20 (40 μL) | 200 μL |
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| FBXO42-SPATA21-20-GRAQ | 20 (40 μL) | 200 μL |
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| FBXO42-SPATA21-20-AQRE | 20 (40 μL) | 200 μL |
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| FBXO42-SPATA21-20-AQOR | 20 (40 μL) | 200 μL |
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| FBXO42-SPATA21-20-AQGO | 20 (40 μL) | 200 μL |
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| FBXO42-SPATA21-20-AQGR | 20 (40 μL) | 200 μL |
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| FBXO42-SPATA21-20-AQAQ | 20 (40 μL) | 200 μL |
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FBXO42 Gene Summary
Members of the F-box protein family, such as FBXO42, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (SKP1A; MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Dec 2010]
Gene Name: F-box Protein 42
Chromosome: CHR1: 16576558 -16678948
Locus: 1p36.13
SPATA21 Gene Summary
The Spermatogenesis Associated 21 (SPATA21) gene is located on chr1 :16725137-16763919 at 1p36.13.
Gene Name: Spermatogenesis Associated 21
Chromosome: CHR1: 16725137 -16763919
Locus: 1p36.13
Gene Diseases
The FBXO42 SPATA21 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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