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FBXO34-ATG7 Fusion FISH Probe

The FBXO34-ATG7 Fusion FISH Probe is used to confirm a fusion of the FBXO34 and ATG7 genes. The fusion of the FBXO34 and ATG7 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
FBXO34-ATG7-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
FBXO34-ATG7-20-RERE 20 (40 μL) 200 μL
FBXO34-ATG7-20-REOR 20 (40 μL) 200 μL
FBXO34-ATG7-20-REGO 20 (40 μL) 200 μL
FBXO34-ATG7-20-REGR 20 (40 μL) 200 μL
FBXO34-ATG7-20-REAQ 20 (40 μL) 200 μL
FBXO34-ATG7-20-ORRE 20 (40 μL) 200 μL
FBXO34-ATG7-20-OROR 20 (40 μL) 200 μL
FBXO34-ATG7-20-ORGO 20 (40 μL) 200 μL
FBXO34-ATG7-20-ORAQ 20 (40 μL) 200 μL
FBXO34-ATG7-20-GORE 20 (40 μL) 200 μL
FBXO34-ATG7-20-GOOR 20 (40 μL) 200 μL
FBXO34-ATG7-20-GOGO 20 (40 μL) 200 μL
FBXO34-ATG7-20-GOGR 20 (40 μL) 200 μL
FBXO34-ATG7-20-GOAQ 20 (40 μL) 200 μL
FBXO34-ATG7-20-GRRE 20 (40 μL) 200 μL
FBXO34-ATG7-20-GROR 20 (40 μL) 200 μL
FBXO34-ATG7-20-GRGO 20 (40 μL) 200 μL
FBXO34-ATG7-20-GRGR 20 (40 μL) 200 μL
FBXO34-ATG7-20-GRAQ 20 (40 μL) 200 μL
FBXO34-ATG7-20-AQRE 20 (40 μL) 200 μL
FBXO34-ATG7-20-AQOR 20 (40 μL) 200 μL
FBXO34-ATG7-20-AQGO 20 (40 μL) 200 μL
FBXO34-ATG7-20-AQGR 20 (40 μL) 200 μL
FBXO34-ATG7-20-AQAQ 20 (40 μL) 200 μL

ATG7 Gene Summary

This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

Gene Name: Autophagy Related 7

Chromosome: CHR3: 11314009 -11599139

Locus: 3p25.3

FBXO34 Gene Summary

Members of the F-box protein family, such as FBXO34, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]

Gene Name: F-box Protein 34

Chromosome: CHR14: 55738020 -55820329

Locus: 14q22.3

Gene Diseases

The FBXO34 ATG7 Fusion has been associated with the following diseases:

Disease Name
Prostate Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.