FBXO34-ATG7 Fusion FISH Probe
The FBXO34-ATG7 Fusion FISH Probe is used to confirm a fusion of the FBXO34 and ATG7 genes. The fusion of the FBXO34 and ATG7 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FBXO34-ATG7-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FBXO34-ATG7-20-RERE | 20 (40 μL) | 200 μL |
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| FBXO34-ATG7-20-REOR | 20 (40 μL) | 200 μL |
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| FBXO34-ATG7-20-REGO | 20 (40 μL) | 200 μL |
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| FBXO34-ATG7-20-REGR | 20 (40 μL) | 200 μL |
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| FBXO34-ATG7-20-REAQ | 20 (40 μL) | 200 μL |
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| FBXO34-ATG7-20-ORRE | 20 (40 μL) | 200 μL |
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| FBXO34-ATG7-20-OROR | 20 (40 μL) | 200 μL |
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| FBXO34-ATG7-20-ORGO | 20 (40 μL) | 200 μL |
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| FBXO34-ATG7-20-ORAQ | 20 (40 μL) | 200 μL |
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| FBXO34-ATG7-20-GORE | 20 (40 μL) | 200 μL |
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| FBXO34-ATG7-20-GOOR | 20 (40 μL) | 200 μL |
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| FBXO34-ATG7-20-GOGO | 20 (40 μL) | 200 μL |
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| FBXO34-ATG7-20-GOGR | 20 (40 μL) | 200 μL |
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| FBXO34-ATG7-20-GOAQ | 20 (40 μL) | 200 μL |
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| FBXO34-ATG7-20-GRRE | 20 (40 μL) | 200 μL |
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| FBXO34-ATG7-20-GROR | 20 (40 μL) | 200 μL |
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| FBXO34-ATG7-20-GRGO | 20 (40 μL) | 200 μL |
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| FBXO34-ATG7-20-GRGR | 20 (40 μL) | 200 μL |
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| FBXO34-ATG7-20-GRAQ | 20 (40 μL) | 200 μL |
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| FBXO34-ATG7-20-AQRE | 20 (40 μL) | 200 μL |
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| FBXO34-ATG7-20-AQOR | 20 (40 μL) | 200 μL |
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| FBXO34-ATG7-20-AQGO | 20 (40 μL) | 200 μL |
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| FBXO34-ATG7-20-AQGR | 20 (40 μL) | 200 μL |
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| FBXO34-ATG7-20-AQAQ | 20 (40 μL) | 200 μL |
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ATG7 Gene Summary
This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Gene Name: Autophagy Related 7
Chromosome: CHR3: 11314009 -11599139
Locus: 3p25.3
FBXO34 Gene Summary
Members of the F-box protein family, such as FBXO34, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
Gene Name: F-box Protein 34
Chromosome: CHR14: 55738020 -55820329
Locus: 14q22.3
Gene Diseases
The FBXO34 ATG7 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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