FBXO28-LYZL2 Fusion FISH Probe
The FBXO28-LYZL2 Fusion FISH Probe is used to confirm a fusion of the FBXO28 and LYZL2 genes. The fusion of the FBXO28 and LYZL2 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FBXO28-LYZL2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FBXO28-LYZL2-20-RERE | 20 (40 μL) | 200 μL |
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| FBXO28-LYZL2-20-REOR | 20 (40 μL) | 200 μL |
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| FBXO28-LYZL2-20-REGO | 20 (40 μL) | 200 μL |
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| FBXO28-LYZL2-20-REGR | 20 (40 μL) | 200 μL |
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| FBXO28-LYZL2-20-REAQ | 20 (40 μL) | 200 μL |
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| FBXO28-LYZL2-20-ORRE | 20 (40 μL) | 200 μL |
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| FBXO28-LYZL2-20-OROR | 20 (40 μL) | 200 μL |
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| FBXO28-LYZL2-20-ORGO | 20 (40 μL) | 200 μL |
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| FBXO28-LYZL2-20-ORAQ | 20 (40 μL) | 200 μL |
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| FBXO28-LYZL2-20-GORE | 20 (40 μL) | 200 μL |
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| FBXO28-LYZL2-20-GOOR | 20 (40 μL) | 200 μL |
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| FBXO28-LYZL2-20-GOGO | 20 (40 μL) | 200 μL |
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| FBXO28-LYZL2-20-GOGR | 20 (40 μL) | 200 μL |
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| FBXO28-LYZL2-20-GOAQ | 20 (40 μL) | 200 μL |
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| FBXO28-LYZL2-20-GRRE | 20 (40 μL) | 200 μL |
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| FBXO28-LYZL2-20-GROR | 20 (40 μL) | 200 μL |
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| FBXO28-LYZL2-20-GRGO | 20 (40 μL) | 200 μL |
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| FBXO28-LYZL2-20-GRGR | 20 (40 μL) | 200 μL |
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| FBXO28-LYZL2-20-GRAQ | 20 (40 μL) | 200 μL |
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| FBXO28-LYZL2-20-AQRE | 20 (40 μL) | 200 μL |
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| FBXO28-LYZL2-20-AQOR | 20 (40 μL) | 200 μL |
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| FBXO28-LYZL2-20-AQGO | 20 (40 μL) | 200 μL |
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| FBXO28-LYZL2-20-AQGR | 20 (40 μL) | 200 μL |
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| FBXO28-LYZL2-20-AQAQ | 20 (40 μL) | 200 μL |
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FBXO28 Gene Summary
Members of the F-box protein family, such as FBXO28, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
Gene Name: F-box Protein 28
Chromosome: CHR1: 224301790 -224349749
Locus: 1q42.11
LYZL2 Gene Summary
Lysozymes (see LYZ; MIM 153450), especially C-type lysozymes, are well-recognized bacteriolytic factors widely distributed in the animal kingdom and play a mainly protective role in host defense. LYZL2 is a member of a family of lysozyme-like genes (Zhang et al., 2005 [PubMed 16014814]).[supplied by OMIM, Apr 2009]
Gene Name: Lysozyme Like 2
Chromosome: CHR10: 30900707 -30918647
Locus: 10p11.23
Gene Diseases
The FBXO28 LYZL2 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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