FBXO17-OSBPL6 Fusion FISH Probe
The FBXO17-OSBPL6 Fusion FISH Probe is used to confirm a fusion of the FBXO17 and OSBPL6 genes. The fusion of the FBXO17 and OSBPL6 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FBXO17-OSBPL6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FBXO17-OSBPL6-20-RERE | 20 (40 μL) | 200 μL |
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| FBXO17-OSBPL6-20-REOR | 20 (40 μL) | 200 μL |
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| FBXO17-OSBPL6-20-REGO | 20 (40 μL) | 200 μL |
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| FBXO17-OSBPL6-20-REGR | 20 (40 μL) | 200 μL |
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| FBXO17-OSBPL6-20-REAQ | 20 (40 μL) | 200 μL |
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| FBXO17-OSBPL6-20-ORRE | 20 (40 μL) | 200 μL |
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| FBXO17-OSBPL6-20-OROR | 20 (40 μL) | 200 μL |
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| FBXO17-OSBPL6-20-ORGO | 20 (40 μL) | 200 μL |
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| FBXO17-OSBPL6-20-ORAQ | 20 (40 μL) | 200 μL |
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| FBXO17-OSBPL6-20-GORE | 20 (40 μL) | 200 μL |
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| FBXO17-OSBPL6-20-GOOR | 20 (40 μL) | 200 μL |
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| FBXO17-OSBPL6-20-GOGO | 20 (40 μL) | 200 μL |
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| FBXO17-OSBPL6-20-GOGR | 20 (40 μL) | 200 μL |
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| FBXO17-OSBPL6-20-GOAQ | 20 (40 μL) | 200 μL |
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| FBXO17-OSBPL6-20-GRRE | 20 (40 μL) | 200 μL |
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| FBXO17-OSBPL6-20-GROR | 20 (40 μL) | 200 μL |
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| FBXO17-OSBPL6-20-GRGO | 20 (40 μL) | 200 μL |
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| FBXO17-OSBPL6-20-GRGR | 20 (40 μL) | 200 μL |
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| FBXO17-OSBPL6-20-GRAQ | 20 (40 μL) | 200 μL |
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| FBXO17-OSBPL6-20-AQRE | 20 (40 μL) | 200 μL |
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| FBXO17-OSBPL6-20-AQOR | 20 (40 μL) | 200 μL |
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| FBXO17-OSBPL6-20-AQGO | 20 (40 μL) | 200 μL |
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| FBXO17-OSBPL6-20-AQGR | 20 (40 μL) | 200 μL |
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| FBXO17-OSBPL6-20-AQAQ | 20 (40 μL) | 200 μL |
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OSBPL6 Gene Summary
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Name: Oxysterol Binding Protein Like 6
Chromosome: CHR2: 179059207 -179264160
Locus: 2q31.2
FBXO17 Gene Summary
This gene encodes a member of the F-box protein family which is characterized by the F-box motif. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it contains an F-box domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Gene Name: F-box Protein 17
Chromosome: CHR19: 39432041 -39466380
Locus: 19q13.2
Gene Diseases
The FBXO17 OSBPL6 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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