FBXL5-RAB28 Fusion FISH Probe
The FBXL5-RAB28 Fusion FISH Probe is used to confirm a fusion of the FBXL5 and RAB28 genes. The fusion of the FBXL5 and RAB28 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FBXL5-RAB28-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FBXL5-RAB28-20-RERE | 20 (40 μL) | 200 μL |
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| FBXL5-RAB28-20-REOR | 20 (40 μL) | 200 μL |
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| FBXL5-RAB28-20-REGO | 20 (40 μL) | 200 μL |
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| FBXL5-RAB28-20-REGR | 20 (40 μL) | 200 μL |
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| FBXL5-RAB28-20-REAQ | 20 (40 μL) | 200 μL |
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| FBXL5-RAB28-20-ORRE | 20 (40 μL) | 200 μL |
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| FBXL5-RAB28-20-OROR | 20 (40 μL) | 200 μL |
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| FBXL5-RAB28-20-ORGO | 20 (40 μL) | 200 μL |
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| FBXL5-RAB28-20-ORAQ | 20 (40 μL) | 200 μL |
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| FBXL5-RAB28-20-GORE | 20 (40 μL) | 200 μL |
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| FBXL5-RAB28-20-GOOR | 20 (40 μL) | 200 μL |
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| FBXL5-RAB28-20-GOGO | 20 (40 μL) | 200 μL |
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| FBXL5-RAB28-20-GOGR | 20 (40 μL) | 200 μL |
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| FBXL5-RAB28-20-GOAQ | 20 (40 μL) | 200 μL |
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| FBXL5-RAB28-20-GRRE | 20 (40 μL) | 200 μL |
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| FBXL5-RAB28-20-GROR | 20 (40 μL) | 200 μL |
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| FBXL5-RAB28-20-GRGO | 20 (40 μL) | 200 μL |
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| FBXL5-RAB28-20-GRGR | 20 (40 μL) | 200 μL |
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| FBXL5-RAB28-20-GRAQ | 20 (40 μL) | 200 μL |
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| FBXL5-RAB28-20-AQRE | 20 (40 μL) | 200 μL |
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| FBXL5-RAB28-20-AQOR | 20 (40 μL) | 200 μL |
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| FBXL5-RAB28-20-AQGO | 20 (40 μL) | 200 μL |
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| FBXL5-RAB28-20-AQGR | 20 (40 μL) | 200 μL |
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| FBXL5-RAB28-20-AQAQ | 20 (40 μL) | 200 μL |
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RAB28 Gene Summary
This gene encodes a member of the Rab subfamily of Ras-related small GTPases. The encoded protein may be involved in regulating intracellular trafficking. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 9 and X. [provided by RefSeq, Apr 2009]
Gene Name: RAB28, Member RAS Oncogene Family
Chromosome: CHR4: 13369346 -13485989
Locus: 4p15.33
FBXL5 Gene Summary
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Aug 2010]
Gene Name: F-box And Leucine Rich Repeat Protein 5
Chromosome: CHR4: 15606006 -15657035
Locus: 4p15.32
Gene Diseases
The FBXL5 RAB28 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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