FBXL20-LRSAM1 Fusion FISH Probe
The FBXL20-LRSAM1 Fusion FISH Probe is used to confirm a fusion of the FBXL20 and LRSAM1 genes. The fusion of the FBXL20 and LRSAM1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FBXL20-LRSAM1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| FBXL20-LRSAM1-20-RERE | 20 (40 μL) | 200 μL |
|
|
| FBXL20-LRSAM1-20-REOR | 20 (40 μL) | 200 μL |
|
|
| FBXL20-LRSAM1-20-REGO | 20 (40 μL) | 200 μL |
|
|
| FBXL20-LRSAM1-20-REGR | 20 (40 μL) | 200 μL |
|
|
| FBXL20-LRSAM1-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| FBXL20-LRSAM1-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| FBXL20-LRSAM1-20-OROR | 20 (40 μL) | 200 μL |
|
|
| FBXL20-LRSAM1-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| FBXL20-LRSAM1-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| FBXL20-LRSAM1-20-GORE | 20 (40 μL) | 200 μL |
|
|
| FBXL20-LRSAM1-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| FBXL20-LRSAM1-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| FBXL20-LRSAM1-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| FBXL20-LRSAM1-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| FBXL20-LRSAM1-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| FBXL20-LRSAM1-20-GROR | 20 (40 μL) | 200 μL |
|
|
| FBXL20-LRSAM1-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| FBXL20-LRSAM1-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| FBXL20-LRSAM1-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| FBXL20-LRSAM1-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| FBXL20-LRSAM1-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| FBXL20-LRSAM1-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| FBXL20-LRSAM1-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| FBXL20-LRSAM1-20-AQAQ | 20 (40 μL) | 200 μL |
|
FBXL20 Gene Summary
Members of the F-box protein family, such as FBXL20, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
Gene Name: F-box And Leucine Rich Repeat Protein 20
Chromosome: CHR17: 37408896 -37557909
Locus: 17q12
LRSAM1 Gene Summary
This gene encodes a ring finger protein involved in a variety of functions, including regulation of signaling pathways and cell adhesion, mediation of self-ubiquitylation, and involvement in cargo sorting during receptor endocytosis. Mutations in this gene have been associated with Charcot-Marie-Tooth disease. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jan 2012]
Gene Name: Leucine Rich Repeat And Sterile Alpha Motif Containing 1
Chromosome: CHR9: 130213764 -130265780
Locus: 9q33.3-q34.11
Gene Diseases
The FBXL20 LRSAM1 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|