FBXL20-GDPD5 Fusion FISH Probe
The FBXL20-GDPD5 Fusion FISH Probe is used to confirm a fusion of the FBXL20 and GDPD5 genes. The fusion of the FBXL20 and GDPD5 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FBXL20-GDPD5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FBXL20-GDPD5-20-RERE | 20 (40 μL) | 200 μL |
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| FBXL20-GDPD5-20-REOR | 20 (40 μL) | 200 μL |
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| FBXL20-GDPD5-20-REGO | 20 (40 μL) | 200 μL |
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| FBXL20-GDPD5-20-REGR | 20 (40 μL) | 200 μL |
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| FBXL20-GDPD5-20-REAQ | 20 (40 μL) | 200 μL |
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| FBXL20-GDPD5-20-ORRE | 20 (40 μL) | 200 μL |
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| FBXL20-GDPD5-20-OROR | 20 (40 μL) | 200 μL |
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| FBXL20-GDPD5-20-ORGO | 20 (40 μL) | 200 μL |
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| FBXL20-GDPD5-20-ORAQ | 20 (40 μL) | 200 μL |
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| FBXL20-GDPD5-20-GORE | 20 (40 μL) | 200 μL |
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| FBXL20-GDPD5-20-GOOR | 20 (40 μL) | 200 μL |
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| FBXL20-GDPD5-20-GOGO | 20 (40 μL) | 200 μL |
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| FBXL20-GDPD5-20-GOGR | 20 (40 μL) | 200 μL |
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| FBXL20-GDPD5-20-GOAQ | 20 (40 μL) | 200 μL |
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| FBXL20-GDPD5-20-GRRE | 20 (40 μL) | 200 μL |
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| FBXL20-GDPD5-20-GROR | 20 (40 μL) | 200 μL |
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| FBXL20-GDPD5-20-GRGO | 20 (40 μL) | 200 μL |
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| FBXL20-GDPD5-20-GRGR | 20 (40 μL) | 200 μL |
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| FBXL20-GDPD5-20-GRAQ | 20 (40 μL) | 200 μL |
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| FBXL20-GDPD5-20-AQRE | 20 (40 μL) | 200 μL |
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| FBXL20-GDPD5-20-AQOR | 20 (40 μL) | 200 μL |
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| FBXL20-GDPD5-20-AQGO | 20 (40 μL) | 200 μL |
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| FBXL20-GDPD5-20-AQGR | 20 (40 μL) | 200 μL |
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| FBXL20-GDPD5-20-AQAQ | 20 (40 μL) | 200 μL |
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GDPD5 Gene Summary
Glycerophosphodiester phosphodiesterases (GDPDs; EC 3.1.4.46), such as GDPD5, are involved in glycerol metabolism (Lang et al., 2008 [PubMed 17578682]).[supplied by OMIM, Jan 2010]
Gene Name: Glycerophosphodiester Phosphodiesterase Domain Containing 5
Chromosome: CHR11: 75145684 -75236599
Locus: 11q13.4-q13.5
FBXL20 Gene Summary
Members of the F-box protein family, such as FBXL20, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
Gene Name: F-box And Leucine Rich Repeat Protein 20
Chromosome: CHR17: 37408896 -37557909
Locus: 17q12
Gene Diseases
The FBXL20 GDPD5 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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