FBXL2-KIF9 Fusion FISH Probe
The FBXL2-KIF9 Fusion FISH Probe is used to confirm a fusion of the FBXL2 and KIF9 genes. The fusion of the FBXL2 and KIF9 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FBXL2-KIF9-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FBXL2-KIF9-20-RERE | 20 (40 μL) | 200 μL |
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| FBXL2-KIF9-20-REOR | 20 (40 μL) | 200 μL |
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| FBXL2-KIF9-20-REGO | 20 (40 μL) | 200 μL |
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| FBXL2-KIF9-20-REGR | 20 (40 μL) | 200 μL |
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| FBXL2-KIF9-20-REAQ | 20 (40 μL) | 200 μL |
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| FBXL2-KIF9-20-ORRE | 20 (40 μL) | 200 μL |
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| FBXL2-KIF9-20-OROR | 20 (40 μL) | 200 μL |
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| FBXL2-KIF9-20-ORGO | 20 (40 μL) | 200 μL |
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| FBXL2-KIF9-20-ORAQ | 20 (40 μL) | 200 μL |
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| FBXL2-KIF9-20-GORE | 20 (40 μL) | 200 μL |
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| FBXL2-KIF9-20-GOOR | 20 (40 μL) | 200 μL |
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| FBXL2-KIF9-20-GOGO | 20 (40 μL) | 200 μL |
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| FBXL2-KIF9-20-GOGR | 20 (40 μL) | 200 μL |
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| FBXL2-KIF9-20-GOAQ | 20 (40 μL) | 200 μL |
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| FBXL2-KIF9-20-GRRE | 20 (40 μL) | 200 μL |
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| FBXL2-KIF9-20-GROR | 20 (40 μL) | 200 μL |
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| FBXL2-KIF9-20-GRGO | 20 (40 μL) | 200 μL |
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| FBXL2-KIF9-20-GRGR | 20 (40 μL) | 200 μL |
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| FBXL2-KIF9-20-GRAQ | 20 (40 μL) | 200 μL |
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| FBXL2-KIF9-20-AQRE | 20 (40 μL) | 200 μL |
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| FBXL2-KIF9-20-AQOR | 20 (40 μL) | 200 μL |
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| FBXL2-KIF9-20-AQGO | 20 (40 μL) | 200 μL |
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| FBXL2-KIF9-20-AQGR | 20 (40 μL) | 200 μL |
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| FBXL2-KIF9-20-AQAQ | 20 (40 μL) | 200 μL |
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FBXL2 Gene Summary
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains 12 tandem leucine-rich repeats. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
Gene Name: F-box And Leucine Rich Repeat Protein 2
Chromosome: CHR3: 33318933 -33428757
Locus: 3p22.3
KIF9 Gene Summary
The Kinesin Family Member 9 (KIF9) gene is located on chr3 :47269515-47324337 at 3p21.31.
Gene Name: Kinesin Family Member 9
Chromosome: CHR3: 47269515 -47324337
Locus: 3p21.31
Gene Diseases
The FBXL2 KIF9 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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