FBXL18-PHF12 Fusion FISH Probe
The FBXL18-PHF12 Fusion FISH Probe is used to confirm a fusion of the FBXL18 and PHF12 genes. The fusion of the FBXL18 and PHF12 genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FBXL18-PHF12-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FBXL18-PHF12-20-RERE | 20 (40 μL) | 200 μL |
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| FBXL18-PHF12-20-REOR | 20 (40 μL) | 200 μL |
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| FBXL18-PHF12-20-REGO | 20 (40 μL) | 200 μL |
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| FBXL18-PHF12-20-REGR | 20 (40 μL) | 200 μL |
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| FBXL18-PHF12-20-REAQ | 20 (40 μL) | 200 μL |
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| FBXL18-PHF12-20-ORRE | 20 (40 μL) | 200 μL |
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| FBXL18-PHF12-20-OROR | 20 (40 μL) | 200 μL |
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| FBXL18-PHF12-20-ORGO | 20 (40 μL) | 200 μL |
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| FBXL18-PHF12-20-ORAQ | 20 (40 μL) | 200 μL |
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| FBXL18-PHF12-20-GORE | 20 (40 μL) | 200 μL |
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| FBXL18-PHF12-20-GOOR | 20 (40 μL) | 200 μL |
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| FBXL18-PHF12-20-GOGO | 20 (40 μL) | 200 μL |
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| FBXL18-PHF12-20-GOGR | 20 (40 μL) | 200 μL |
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| FBXL18-PHF12-20-GOAQ | 20 (40 μL) | 200 μL |
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| FBXL18-PHF12-20-GRRE | 20 (40 μL) | 200 μL |
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| FBXL18-PHF12-20-GROR | 20 (40 μL) | 200 μL |
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| FBXL18-PHF12-20-GRGO | 20 (40 μL) | 200 μL |
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| FBXL18-PHF12-20-GRGR | 20 (40 μL) | 200 μL |
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| FBXL18-PHF12-20-GRAQ | 20 (40 μL) | 200 μL |
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| FBXL18-PHF12-20-AQRE | 20 (40 μL) | 200 μL |
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| FBXL18-PHF12-20-AQOR | 20 (40 μL) | 200 μL |
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| FBXL18-PHF12-20-AQGO | 20 (40 μL) | 200 μL |
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| FBXL18-PHF12-20-AQGR | 20 (40 μL) | 200 μL |
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| FBXL18-PHF12-20-AQAQ | 20 (40 μL) | 200 μL |
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PHF12 Gene Summary
The PHD Finger Protein 12 (PHF12) gene is located on chr17 :27232270-27278508 at 17q11.2.
Gene Name: PHD Finger Protein 12
Chromosome: CHR17: 27232270 -27278508
Locus: 17q11.2
FBXL18 Gene Summary
The protein encoded by this gene is a member of a family of proteins that contain an approximately 40-amino acid F-box motif. This motif is important for interaction with SKP1 and for targeting some proteins for degradation. The encoded protein has been shown to control the cellular level of FBXL7, a protein that induces mitotic arrest, by targeting it for polyubiquitylation and proteasomal degradation. Members of the F-box protein family, such as FBXL18, are characterized by an approximately 40-amino acid F-box motif. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains. [provided by RefSeq, Mar 2016]
Gene Name: F-box And Leucine Rich Repeat Protein 18
Chromosome: CHR7: 5515427 -5553399
Locus: 7p22.1
Gene Diseases
The FBXL18 PHF12 Fusion has been associated with the following diseases:
| Disease Name |
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| Esophageal Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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