FBN1-EIF3B Fusion FISH Probe
The FBN1-EIF3B Fusion FISH Probe is used to confirm a fusion of the FBN1 and EIF3B genes. The fusion of the FBN1 and EIF3B genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FBN1-EIF3B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FBN1-EIF3B-20-RERE | 20 (40 μL) | 200 μL |
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| FBN1-EIF3B-20-REOR | 20 (40 μL) | 200 μL |
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| FBN1-EIF3B-20-REGO | 20 (40 μL) | 200 μL |
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| FBN1-EIF3B-20-REGR | 20 (40 μL) | 200 μL |
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| FBN1-EIF3B-20-REAQ | 20 (40 μL) | 200 μL |
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| FBN1-EIF3B-20-ORRE | 20 (40 μL) | 200 μL |
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| FBN1-EIF3B-20-OROR | 20 (40 μL) | 200 μL |
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| FBN1-EIF3B-20-ORGO | 20 (40 μL) | 200 μL |
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| FBN1-EIF3B-20-ORAQ | 20 (40 μL) | 200 μL |
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| FBN1-EIF3B-20-GORE | 20 (40 μL) | 200 μL |
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| FBN1-EIF3B-20-GOOR | 20 (40 μL) | 200 μL |
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| FBN1-EIF3B-20-GOGO | 20 (40 μL) | 200 μL |
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| FBN1-EIF3B-20-GOGR | 20 (40 μL) | 200 μL |
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| FBN1-EIF3B-20-GOAQ | 20 (40 μL) | 200 μL |
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| FBN1-EIF3B-20-GRRE | 20 (40 μL) | 200 μL |
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| FBN1-EIF3B-20-GROR | 20 (40 μL) | 200 μL |
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| FBN1-EIF3B-20-GRGO | 20 (40 μL) | 200 μL |
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| FBN1-EIF3B-20-GRGR | 20 (40 μL) | 200 μL |
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| FBN1-EIF3B-20-GRAQ | 20 (40 μL) | 200 μL |
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| FBN1-EIF3B-20-AQRE | 20 (40 μL) | 200 μL |
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| FBN1-EIF3B-20-AQOR | 20 (40 μL) | 200 μL |
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| FBN1-EIF3B-20-AQGO | 20 (40 μL) | 200 μL |
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| FBN1-EIF3B-20-AQGR | 20 (40 μL) | 200 μL |
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| FBN1-EIF3B-20-AQAQ | 20 (40 μL) | 200 μL |
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FBN1 Gene Summary
This gene encodes a member of the fibrillin family of proteins. The encoded preproprotein is proteolytically processed to generate two proteins including the extracellular matrix component fibrillin-1 and the protein hormone asprosin. Fibrillin-1 is an extracellular matrix glycoprotein that serves as a structural component of calcium-binding microfibrils. These microfibrils provide force-bearing structural support in elastic and nonelastic connective tissue throughout the body. Asprosin, secreted by white adipose tissue, has been shown to regulate glucose homeostasis. Mutations in this gene are associated with Marfan syndrome and the related MASS phenotype, as well as ectopia lentis syndrome, Weill-Marchesani syndrome, Shprintzen-Goldberg syndrome and neonatal progeroid syndrome. [provided by RefSeq, Apr 2016]
Gene Name: Fibrillin 1
Chromosome: CHR15: 48700502 -48937985
Locus: 15q21.1
EIF3B Gene Summary
The Eukaryotic Translation Initiation Factor 3 Subunit B (EIF3B) gene is located on chr7 :2394473-2420377 at 7p22.3.
Gene Name: Eukaryotic Translation Initiation Factor 3 Subunit B
Chromosome: CHR7: 2394473 -2420377
Locus: 7p22.3
Gene Diseases
The FBN1 EIF3B Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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