FASTK-GNGT1 Fusion FISH Probe
The FASTK-GNGT1 Fusion FISH Probe is used to confirm a fusion of the FASTK and GNGT1 genes. The fusion of the FASTK and GNGT1 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FASTK-GNGT1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FASTK-GNGT1-20-RERE | 20 (40 μL) | 200 μL |
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| FASTK-GNGT1-20-REOR | 20 (40 μL) | 200 μL |
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| FASTK-GNGT1-20-REGO | 20 (40 μL) | 200 μL |
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| FASTK-GNGT1-20-REGR | 20 (40 μL) | 200 μL |
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| FASTK-GNGT1-20-REAQ | 20 (40 μL) | 200 μL |
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| FASTK-GNGT1-20-ORRE | 20 (40 μL) | 200 μL |
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| FASTK-GNGT1-20-OROR | 20 (40 μL) | 200 μL |
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| FASTK-GNGT1-20-ORGO | 20 (40 μL) | 200 μL |
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| FASTK-GNGT1-20-ORAQ | 20 (40 μL) | 200 μL |
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| FASTK-GNGT1-20-GORE | 20 (40 μL) | 200 μL |
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| FASTK-GNGT1-20-GOOR | 20 (40 μL) | 200 μL |
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| FASTK-GNGT1-20-GOGO | 20 (40 μL) | 200 μL |
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| FASTK-GNGT1-20-GOGR | 20 (40 μL) | 200 μL |
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| FASTK-GNGT1-20-GOAQ | 20 (40 μL) | 200 μL |
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| FASTK-GNGT1-20-GRRE | 20 (40 μL) | 200 μL |
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| FASTK-GNGT1-20-GROR | 20 (40 μL) | 200 μL |
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| FASTK-GNGT1-20-GRGO | 20 (40 μL) | 200 μL |
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| FASTK-GNGT1-20-GRGR | 20 (40 μL) | 200 μL |
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| FASTK-GNGT1-20-GRAQ | 20 (40 μL) | 200 μL |
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| FASTK-GNGT1-20-AQRE | 20 (40 μL) | 200 μL |
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| FASTK-GNGT1-20-AQOR | 20 (40 μL) | 200 μL |
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| FASTK-GNGT1-20-AQGO | 20 (40 μL) | 200 μL |
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| FASTK-GNGT1-20-AQGR | 20 (40 μL) | 200 μL |
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| FASTK-GNGT1-20-AQAQ | 20 (40 μL) | 200 μL |
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GNGT1 Gene Summary
This gene encodes the gamma subunit of transducin, a guanine nucleotide-binding protein (G protein) that is found in rod outer segments. Transducin, also known as GMPase, mediates the activation of a cyclic GTP-specific (guanosine monophosphate) phosphodiesterase by rhodopsin. [provided by RefSeq, Jul 2016]
Gene Name: G Protein Subunit Gamma Transducin 1
Chromosome: CHR7: 93535819 -93540485
Locus: 7q21.3
FASTK Gene Summary
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined. [provided by RefSeq, Jul 2008]
Gene Name: Fas Activated Serine/threonine Kinase
Chromosome: CHR7: 150773707 -150777951
Locus: 7q36.1
Gene Diseases
The FASTK GNGT1 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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