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FARS2-KPNA4 Fusion FISH Probe

The FARS2-KPNA4 Fusion FISH Probe is used to confirm a fusion of the FARS2 and KPNA4 genes. The fusion of the FARS2 and KPNA4 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
FARS2-KPNA4-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
FARS2-KPNA4-20-RERE 20 (40 μL) 200 μL
FARS2-KPNA4-20-REOR 20 (40 μL) 200 μL
FARS2-KPNA4-20-REGO 20 (40 μL) 200 μL
FARS2-KPNA4-20-REGR 20 (40 μL) 200 μL
FARS2-KPNA4-20-REAQ 20 (40 μL) 200 μL
FARS2-KPNA4-20-ORRE 20 (40 μL) 200 μL
FARS2-KPNA4-20-OROR 20 (40 μL) 200 μL
FARS2-KPNA4-20-ORGO 20 (40 μL) 200 μL
FARS2-KPNA4-20-ORAQ 20 (40 μL) 200 μL
FARS2-KPNA4-20-GORE 20 (40 μL) 200 μL
FARS2-KPNA4-20-GOOR 20 (40 μL) 200 μL
FARS2-KPNA4-20-GOGO 20 (40 μL) 200 μL
FARS2-KPNA4-20-GOGR 20 (40 μL) 200 μL
FARS2-KPNA4-20-GOAQ 20 (40 μL) 200 μL
FARS2-KPNA4-20-GRRE 20 (40 μL) 200 μL
FARS2-KPNA4-20-GROR 20 (40 μL) 200 μL
FARS2-KPNA4-20-GRGO 20 (40 μL) 200 μL
FARS2-KPNA4-20-GRGR 20 (40 μL) 200 μL
FARS2-KPNA4-20-GRAQ 20 (40 μL) 200 μL
FARS2-KPNA4-20-AQRE 20 (40 μL) 200 μL
FARS2-KPNA4-20-AQOR 20 (40 μL) 200 μL
FARS2-KPNA4-20-AQGO 20 (40 μL) 200 μL
FARS2-KPNA4-20-AQGR 20 (40 μL) 200 μL
FARS2-KPNA4-20-AQAQ 20 (40 μL) 200 μL

KPNA4 Gene Summary

The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen. [provided by RefSeq, Jul 2008]

Gene Name: Karyopherin Subunit Alpha 4

Chromosome: CHR3: 160212782 -160283376

Locus: 3q25.33

FARS2 Gene Summary

This gene encodes a protein that transfers phenylalanine to its cognate tRNA. This protein localizes to the mitochondrion and plays a role in mitochondrial protein translation. Mutations in this gene can cause combined oxidative phosphorylation deficiency 14 (Alpers encephalopathy). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

Gene Name: Phenylalanyl-tRNA Synthetase 2, Mitochondrial

Chromosome: CHR6: 5261583 -5771816

Locus: 6p25.1

Gene Diseases

The FARS2 KPNA4 Fusion has been associated with the following diseases:

Disease Name
Sarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.