FARS2-GCNT2 Fusion FISH Probe
The FARS2-GCNT2 Fusion FISH Probe is used to confirm a fusion of the FARS2 and GCNT2 genes. The fusion of the FARS2 and GCNT2 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FARS2-GCNT2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FARS2-GCNT2-20-RERE | 20 (40 μL) | 200 μL |
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| FARS2-GCNT2-20-REOR | 20 (40 μL) | 200 μL |
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| FARS2-GCNT2-20-REGO | 20 (40 μL) | 200 μL |
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| FARS2-GCNT2-20-REGR | 20 (40 μL) | 200 μL |
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| FARS2-GCNT2-20-REAQ | 20 (40 μL) | 200 μL |
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| FARS2-GCNT2-20-ORRE | 20 (40 μL) | 200 μL |
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| FARS2-GCNT2-20-OROR | 20 (40 μL) | 200 μL |
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| FARS2-GCNT2-20-ORGO | 20 (40 μL) | 200 μL |
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| FARS2-GCNT2-20-ORAQ | 20 (40 μL) | 200 μL |
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| FARS2-GCNT2-20-GORE | 20 (40 μL) | 200 μL |
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| FARS2-GCNT2-20-GOOR | 20 (40 μL) | 200 μL |
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| FARS2-GCNT2-20-GOGO | 20 (40 μL) | 200 μL |
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| FARS2-GCNT2-20-GOGR | 20 (40 μL) | 200 μL |
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| FARS2-GCNT2-20-GOAQ | 20 (40 μL) | 200 μL |
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| FARS2-GCNT2-20-GRRE | 20 (40 μL) | 200 μL |
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| FARS2-GCNT2-20-GROR | 20 (40 μL) | 200 μL |
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| FARS2-GCNT2-20-GRGO | 20 (40 μL) | 200 μL |
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| FARS2-GCNT2-20-GRGR | 20 (40 μL) | 200 μL |
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| FARS2-GCNT2-20-GRAQ | 20 (40 μL) | 200 μL |
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| FARS2-GCNT2-20-AQRE | 20 (40 μL) | 200 μL |
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| FARS2-GCNT2-20-AQOR | 20 (40 μL) | 200 μL |
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| FARS2-GCNT2-20-AQGO | 20 (40 μL) | 200 μL |
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| FARS2-GCNT2-20-AQGR | 20 (40 μL) | 200 μL |
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| FARS2-GCNT2-20-AQAQ | 20 (40 μL) | 200 μL |
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GCNT2 Gene Summary
This gene encodes the enzyme responsible for formation of the blood group I antigen. The i and I antigens are distinguished by linear and branched poly-N-acetyllactosaminoglycans, respectively. The encoded protein is the I-branching enzyme, a beta-1,6-N-acetylglucosaminyltransferase responsible for the conversion of fetal i antigen to adult I antigen in erythrocytes during embryonic development. Mutations in this gene have been associated with adult i blood group phenotype. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Name: Glucosaminyl (N-acetyl) Transferase 2, I-branching Enzyme (I Blood Group)
Chromosome: CHR6: 10521567 -10629601
Locus: 6p24.3-p24.2
FARS2 Gene Summary
This gene encodes a protein that transfers phenylalanine to its cognate tRNA. This protein localizes to the mitochondrion and plays a role in mitochondrial protein translation. Mutations in this gene can cause combined oxidative phosphorylation deficiency 14 (Alpers encephalopathy). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Gene Name: Phenylalanyl-tRNA Synthetase 2, Mitochondrial
Chromosome: CHR6: 5261583 -5771816
Locus: 6p25.1
Gene Diseases
The FARS2 GCNT2 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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