FANCC-ROR2 Fusion FISH Probe
The FANCC-ROR2 Fusion FISH Probe is used to confirm a fusion of the FANCC and ROR2 genes. The fusion of the FANCC and ROR2 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FANCC-ROR2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FANCC-ROR2-20-RERE | 20 (40 μL) | 200 μL |
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| FANCC-ROR2-20-REOR | 20 (40 μL) | 200 μL |
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| FANCC-ROR2-20-REGO | 20 (40 μL) | 200 μL |
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| FANCC-ROR2-20-REGR | 20 (40 μL) | 200 μL |
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| FANCC-ROR2-20-REAQ | 20 (40 μL) | 200 μL |
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| FANCC-ROR2-20-ORRE | 20 (40 μL) | 200 μL |
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| FANCC-ROR2-20-OROR | 20 (40 μL) | 200 μL |
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| FANCC-ROR2-20-ORGO | 20 (40 μL) | 200 μL |
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| FANCC-ROR2-20-ORAQ | 20 (40 μL) | 200 μL |
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| FANCC-ROR2-20-GORE | 20 (40 μL) | 200 μL |
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| FANCC-ROR2-20-GOOR | 20 (40 μL) | 200 μL |
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| FANCC-ROR2-20-GOGO | 20 (40 μL) | 200 μL |
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| FANCC-ROR2-20-GOGR | 20 (40 μL) | 200 μL |
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| FANCC-ROR2-20-GOAQ | 20 (40 μL) | 200 μL |
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| FANCC-ROR2-20-GRRE | 20 (40 μL) | 200 μL |
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| FANCC-ROR2-20-GROR | 20 (40 μL) | 200 μL |
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| FANCC-ROR2-20-GRGO | 20 (40 μL) | 200 μL |
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| FANCC-ROR2-20-GRGR | 20 (40 μL) | 200 μL |
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| FANCC-ROR2-20-GRAQ | 20 (40 μL) | 200 μL |
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| FANCC-ROR2-20-AQRE | 20 (40 μL) | 200 μL |
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| FANCC-ROR2-20-AQOR | 20 (40 μL) | 200 μL |
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| FANCC-ROR2-20-AQGO | 20 (40 μL) | 200 μL |
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| FANCC-ROR2-20-AQGR | 20 (40 μL) | 200 μL |
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| FANCC-ROR2-20-AQAQ | 20 (40 μL) | 200 μL |
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FANCC Gene Summary
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group C. [provided by RefSeq, Jul 2008]
Gene Name: Fanconi Anemia Complementation Group C
Chromosome: CHR9: 97861335 -98079991
Locus: 9q22.32
ROR2 Gene Summary
The protein encoded by this gene is a receptor protein tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. The protein may be involved in the early formation of the chondrocytes and may be required for cartilage and growth plate development. Mutations in this gene can cause brachydactyly type B, a skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In addition, mutations in this gene can cause the autosomal recessive form of Robinow syndrome, which is characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly, and a dysmorphic facial appearance. [provided by RefSeq, Jul 2008]
Gene Name: Receptor Tyrosine Kinase Like Orphan Receptor 2
Chromosome: CHR9: 94484877 -94712444
Locus: 9q22.31
Gene Diseases
The FANCC ROR2 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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