FANCC-DDX31 Fusion FISH Probe
The FANCC-DDX31 Fusion FISH Probe is used to confirm a fusion of the FANCC and DDX31 genes. The fusion of the FANCC and DDX31 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FANCC-DDX31-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FANCC-DDX31-20-RERE | 20 (40 μL) | 200 μL |
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| FANCC-DDX31-20-REOR | 20 (40 μL) | 200 μL |
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| FANCC-DDX31-20-REGO | 20 (40 μL) | 200 μL |
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| FANCC-DDX31-20-REGR | 20 (40 μL) | 200 μL |
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| FANCC-DDX31-20-REAQ | 20 (40 μL) | 200 μL |
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| FANCC-DDX31-20-ORRE | 20 (40 μL) | 200 μL |
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| FANCC-DDX31-20-OROR | 20 (40 μL) | 200 μL |
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| FANCC-DDX31-20-ORGO | 20 (40 μL) | 200 μL |
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| FANCC-DDX31-20-ORAQ | 20 (40 μL) | 200 μL |
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| FANCC-DDX31-20-GORE | 20 (40 μL) | 200 μL |
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| FANCC-DDX31-20-GOOR | 20 (40 μL) | 200 μL |
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| FANCC-DDX31-20-GOGO | 20 (40 μL) | 200 μL |
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| FANCC-DDX31-20-GOGR | 20 (40 μL) | 200 μL |
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| FANCC-DDX31-20-GOAQ | 20 (40 μL) | 200 μL |
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| FANCC-DDX31-20-GRRE | 20 (40 μL) | 200 μL |
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| FANCC-DDX31-20-GROR | 20 (40 μL) | 200 μL |
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| FANCC-DDX31-20-GRGO | 20 (40 μL) | 200 μL |
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| FANCC-DDX31-20-GRGR | 20 (40 μL) | 200 μL |
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| FANCC-DDX31-20-GRAQ | 20 (40 μL) | 200 μL |
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| FANCC-DDX31-20-AQRE | 20 (40 μL) | 200 μL |
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| FANCC-DDX31-20-AQOR | 20 (40 μL) | 200 μL |
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| FANCC-DDX31-20-AQGO | 20 (40 μL) | 200 μL |
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| FANCC-DDX31-20-AQGR | 20 (40 μL) | 200 μL |
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| FANCC-DDX31-20-AQAQ | 20 (40 μL) | 200 μL |
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FANCC Gene Summary
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group C. [provided by RefSeq, Jul 2008]
Gene Name: Fanconi Anemia Complementation Group C
Chromosome: CHR9: 97861335 -98079991
Locus: 9q22.32
DDX31 Gene Summary
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The function of this member has not been determined. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2016]
Gene Name: DEAD-box Helicase 31
Chromosome: CHR9: 135469675 -135545788
Locus: 9q34.13
Gene Diseases
The FANCC DDX31 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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