FAM98B-RASGRP1 Fusion FISH Probe
The FAM98B-RASGRP1 Fusion FISH Probe is used to confirm a fusion of the FAM98B and RASGRP1 genes. The fusion of the FAM98B and RASGRP1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FAM98B-RASGRP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| FAM98B-RASGRP1-20-RERE | 20 (40 μL) | 200 μL |
|
|
| FAM98B-RASGRP1-20-REOR | 20 (40 μL) | 200 μL |
|
|
| FAM98B-RASGRP1-20-REGO | 20 (40 μL) | 200 μL |
|
|
| FAM98B-RASGRP1-20-REGR | 20 (40 μL) | 200 μL |
|
|
| FAM98B-RASGRP1-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| FAM98B-RASGRP1-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| FAM98B-RASGRP1-20-OROR | 20 (40 μL) | 200 μL |
|
|
| FAM98B-RASGRP1-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| FAM98B-RASGRP1-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| FAM98B-RASGRP1-20-GORE | 20 (40 μL) | 200 μL |
|
|
| FAM98B-RASGRP1-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| FAM98B-RASGRP1-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| FAM98B-RASGRP1-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| FAM98B-RASGRP1-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| FAM98B-RASGRP1-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| FAM98B-RASGRP1-20-GROR | 20 (40 μL) | 200 μL |
|
|
| FAM98B-RASGRP1-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| FAM98B-RASGRP1-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| FAM98B-RASGRP1-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| FAM98B-RASGRP1-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| FAM98B-RASGRP1-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| FAM98B-RASGRP1-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| FAM98B-RASGRP1-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| FAM98B-RASGRP1-20-AQAQ | 20 (40 μL) | 200 μL |
|
RASGRP1 Gene Summary
This gene is a member of a family of genes characterized by the presence of a Ras superfamily guanine nucleotide exchange factor (GEF) domain. It functions as a diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. It activates the Erk/MAP kinase cascade and regulates T-cells and B-cells development, homeostasis and differentiation. Alternatively spliced transcript variants encoding different isoforms have been identified. Altered expression of the different isoforms of this protein may be a cause of susceptibility to systemic lupus erythematosus (SLE). [provided by RefSeq, Jul 2008]
Gene Name: RAS Guanyl Releasing Protein 1
Chromosome: CHR15: 38780301 -38857007
Locus: 15q14
FAM98B Gene Summary
The Family With Sequence Similarity 98 Member B (FAM98B) gene is located on chr15 :38746327-38777063 at 15q14.
Gene Name: Family With Sequence Similarity 98 Member B
Chromosome: CHR15: 38746327 -38777063
Locus: 15q14
Gene Diseases
The FAM98B RASGRP1 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|